Details
| Original language | English |
|---|---|
| Article number | 4300 |
| Journal | MATERIALS |
| Volume | 14 |
| Issue number | 15 |
| Publication status | Published - 31 Jul 2021 |
| Externally published | Yes |
Abstract
To modulate the properties of degradable implants from outside of the human body rep-resents a major challenge in the field of biomaterials. Polylactic acid is one of the most used polymers in biomedical applications, but it tends to lose its mechanical properties too quickly during degradation. In the present study, a way to reinforce poly-L lactic acid (PLLA) with magnetic nano-particles (MNPs) that have the capacity to heat under radiofrequency electromagnetic fields (EMF) is proposed. As mechanical and degradation properties are related to the crystallinity of PLLA, the aim of the work was to explore the possibility of modifying the structure of the polymer through the heating of the reinforcing MNPs by EMF within the biological limit range f·H < 5·× 10 9 Am −1·s −1. Composites were prepared by dispersing MNPs under sonication in a solution of PLLA. The heat released by the MNPs was monitored by an infrared camera and changes in the polymer were ana-lyzed with differential scanning calorimetry and nanoindentation techniques. The crystallinity, hardness, and elastic modulus of nanocomposites increase with EMF treatment.
Keywords
- Biodegradable nanocomposite, Magnetic nanoparticles, PLLA, Radiofrequency electromagnetic field
ASJC Scopus subject areas
- Physics and Astronomy(all)
- Condensed Matter Physics
- Materials Science(all)
- General Materials Science
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In: MATERIALS, Vol. 14, No. 15, 4300, 31.07.2021.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Modulation of Crystallinity through Radiofrequency Electromagnetic Fields in PLLA/Magnetic Nanoparticles Composites: A Proof of Concept
AU - Multigner, Marta
AU - Morales, Irene
AU - Muñoz, Marta
AU - Bonache, Victoria
AU - Giacomone, Fernando
AU - Presa, Patricia de la
AU - Benavente, Rosario
AU - Torres, Belén
AU - Mantovani, Diego
AU - Rams, Joaquín
N1 - Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/7/31
Y1 - 2021/7/31
N2 - To modulate the properties of degradable implants from outside of the human body rep-resents a major challenge in the field of biomaterials. Polylactic acid is one of the most used polymers in biomedical applications, but it tends to lose its mechanical properties too quickly during degradation. In the present study, a way to reinforce poly-L lactic acid (PLLA) with magnetic nano-particles (MNPs) that have the capacity to heat under radiofrequency electromagnetic fields (EMF) is proposed. As mechanical and degradation properties are related to the crystallinity of PLLA, the aim of the work was to explore the possibility of modifying the structure of the polymer through the heating of the reinforcing MNPs by EMF within the biological limit range f·H < 5·× 10 9 Am −1·s −1. Composites were prepared by dispersing MNPs under sonication in a solution of PLLA. The heat released by the MNPs was monitored by an infrared camera and changes in the polymer were ana-lyzed with differential scanning calorimetry and nanoindentation techniques. The crystallinity, hardness, and elastic modulus of nanocomposites increase with EMF treatment.
AB - To modulate the properties of degradable implants from outside of the human body rep-resents a major challenge in the field of biomaterials. Polylactic acid is one of the most used polymers in biomedical applications, but it tends to lose its mechanical properties too quickly during degradation. In the present study, a way to reinforce poly-L lactic acid (PLLA) with magnetic nano-particles (MNPs) that have the capacity to heat under radiofrequency electromagnetic fields (EMF) is proposed. As mechanical and degradation properties are related to the crystallinity of PLLA, the aim of the work was to explore the possibility of modifying the structure of the polymer through the heating of the reinforcing MNPs by EMF within the biological limit range f·H < 5·× 10 9 Am −1·s −1. Composites were prepared by dispersing MNPs under sonication in a solution of PLLA. The heat released by the MNPs was monitored by an infrared camera and changes in the polymer were ana-lyzed with differential scanning calorimetry and nanoindentation techniques. The crystallinity, hardness, and elastic modulus of nanocomposites increase with EMF treatment.
KW - Biodegradable nanocomposite
KW - Magnetic nanoparticles
KW - PLLA
KW - Radiofrequency electromagnetic field
UR - http://www.scopus.com/inward/record.url?scp=85112617023&partnerID=8YFLogxK
U2 - 10.3390/ma14154300
DO - 10.3390/ma14154300
M3 - Article
VL - 14
JO - MATERIALS
JF - MATERIALS
SN - 1996-1944
IS - 15
M1 - 4300
ER -