Details
| Original language | English |
|---|---|
| Pages (from-to) | 121-135 |
| Number of pages | 15 |
| Journal | Journal of biotechnology |
| Volume | 29 |
| Issue number | 1-2 |
| Publication status | Published - May 1993 |
Abstract
The growth of the fungus Trichoderma reesei Rut C30 on cellulosic materials, especially potato pulp, and the enzyme synthesis in batch and fed-batch cultures were investigated by Klingspohn (1990). Based on these experimental data, a comprehensive model was set up describing the uptake of substrate for growth, maintenance and enzyme synthesis including the enzymatic hydrolysis of the substrate (Bader, 1991). The model equations consist of non-linear systems of ordinary differential and algebraic equations. The model parameters were identified by means of the experimental results. The simulation results correspond well with the experimental data. Model computations for different operational conditions show the range of validity and the performance of the model. Possibilities of improvements of the yield and productivity can be deducted.
Keywords
- Enzyme synthesis, Modelling and simulation, Trichoderma reesei
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Immunology and Microbiology(all)
- Applied Microbiology and Biotechnology
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In: Journal of biotechnology, Vol. 29, No. 1-2, 05.1993, p. 121-135.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Modelling and simulation of the growth and enzyme production of Trichoderma reesei Rut C30
AU - Bader, J.
AU - Klingspohn, U.
AU - Bellgardt, K. H.
AU - Schügerl, K.
PY - 1993/5
Y1 - 1993/5
N2 - The growth of the fungus Trichoderma reesei Rut C30 on cellulosic materials, especially potato pulp, and the enzyme synthesis in batch and fed-batch cultures were investigated by Klingspohn (1990). Based on these experimental data, a comprehensive model was set up describing the uptake of substrate for growth, maintenance and enzyme synthesis including the enzymatic hydrolysis of the substrate (Bader, 1991). The model equations consist of non-linear systems of ordinary differential and algebraic equations. The model parameters were identified by means of the experimental results. The simulation results correspond well with the experimental data. Model computations for different operational conditions show the range of validity and the performance of the model. Possibilities of improvements of the yield and productivity can be deducted.
AB - The growth of the fungus Trichoderma reesei Rut C30 on cellulosic materials, especially potato pulp, and the enzyme synthesis in batch and fed-batch cultures were investigated by Klingspohn (1990). Based on these experimental data, a comprehensive model was set up describing the uptake of substrate for growth, maintenance and enzyme synthesis including the enzymatic hydrolysis of the substrate (Bader, 1991). The model equations consist of non-linear systems of ordinary differential and algebraic equations. The model parameters were identified by means of the experimental results. The simulation results correspond well with the experimental data. Model computations for different operational conditions show the range of validity and the performance of the model. Possibilities of improvements of the yield and productivity can be deducted.
KW - Enzyme synthesis
KW - Modelling and simulation
KW - Trichoderma reesei
UR - http://www.scopus.com/inward/record.url?scp=0027196766&partnerID=8YFLogxK
U2 - 10.1016/0168-1656(93)90045-O
DO - 10.1016/0168-1656(93)90045-O
M3 - Article
AN - SCOPUS:0027196766
VL - 29
SP - 121
EP - 135
JO - Journal of biotechnology
JF - Journal of biotechnology
SN - 0168-1656
IS - 1-2
ER -