Details
| Original language | English |
|---|---|
| Pages (from-to) | 953-966 |
| Number of pages | 14 |
| Journal | At-Automatisierungstechnik |
| Volume | 68 |
| Issue number | 11 |
| Early online date | 28 Oct 2020 |
| Publication status | Published - 26 Nov 2020 |
Abstract
Laser photocoagulation is a widely used treatment for a variety of retinal diseases. Temperature-controlled irradiation is a promising approach to enable uniform heating, reduce the risks of over- or undertreatment, and unburden the ophthalmologists from a time consuming manual power titration. In this paper, an approach is proposed for the development of models with different levels of detail, which serve as a basis for improved, more accurate observer and control designs. To this end, we employ a heat diffusion model and propose a suitable discretization and subsequent model reduction procedures. Since the absorption of the laser light can vary strongly at each irradiation site, a method for identifying the absorption coefficient is presented. To identify a parameter in a reduced order model, an optimal interpolatory projection method for parametric systems is used. In order to provide an online identification of the absorption coefficient, we prove and exploit monotonicity of the parameter influence.
Keywords
- identification, parametric model order reduction, retinal photocoagulation
ASJC Scopus subject areas
- Engineering(all)
- Control and Systems Engineering
- Computer Science(all)
- Computer Science Applications
- Engineering(all)
- Electrical and Electronic Engineering
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In: At-Automatisierungstechnik, Vol. 68, No. 11, 26.11.2020, p. 953-966.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Modeling and parameter identification for real-time temperature controlled retinal laser therapies
AU - Kleyman, Viktoria
AU - Gernandt, Hannes
AU - Worthmann, Karl
AU - Abbas, Hossam S.
AU - Brinkmann, Ralf
AU - Müller, Matthias A.
PY - 2020/11/26
Y1 - 2020/11/26
N2 - Laser photocoagulation is a widely used treatment for a variety of retinal diseases. Temperature-controlled irradiation is a promising approach to enable uniform heating, reduce the risks of over- or undertreatment, and unburden the ophthalmologists from a time consuming manual power titration. In this paper, an approach is proposed for the development of models with different levels of detail, which serve as a basis for improved, more accurate observer and control designs. To this end, we employ a heat diffusion model and propose a suitable discretization and subsequent model reduction procedures. Since the absorption of the laser light can vary strongly at each irradiation site, a method for identifying the absorption coefficient is presented. To identify a parameter in a reduced order model, an optimal interpolatory projection method for parametric systems is used. In order to provide an online identification of the absorption coefficient, we prove and exploit monotonicity of the parameter influence.
AB - Laser photocoagulation is a widely used treatment for a variety of retinal diseases. Temperature-controlled irradiation is a promising approach to enable uniform heating, reduce the risks of over- or undertreatment, and unburden the ophthalmologists from a time consuming manual power titration. In this paper, an approach is proposed for the development of models with different levels of detail, which serve as a basis for improved, more accurate observer and control designs. To this end, we employ a heat diffusion model and propose a suitable discretization and subsequent model reduction procedures. Since the absorption of the laser light can vary strongly at each irradiation site, a method for identifying the absorption coefficient is presented. To identify a parameter in a reduced order model, an optimal interpolatory projection method for parametric systems is used. In order to provide an online identification of the absorption coefficient, we prove and exploit monotonicity of the parameter influence.
KW - identification
KW - parametric model order reduction
KW - retinal photocoagulation
UR - http://www.scopus.com/inward/record.url?scp=85095768712&partnerID=8YFLogxK
U2 - 10.1515/auto-2020-0074
DO - 10.1515/auto-2020-0074
M3 - Article
VL - 68
SP - 953
EP - 966
JO - At-Automatisierungstechnik
JF - At-Automatisierungstechnik
SN - 0178-2312
IS - 11
ER -