Details
| Original language | English |
|---|---|
| Pages (from-to) | 1506-1509 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 49 |
| Issue number | 9 |
| Publication status | Published - 8 Jan 2008 |
Abstract
An efficient and facile method for the iodo-functionalization of alkenes 5 and alkynes 6 by using recyclable m-iodosylbenzoic acid (2) was developed. The final products can be easily isolated without any chromatographic purification by simple treatment of the crude mixture with an anionic exchange resin. Unreacted m-iodosylbenzoic acid and reduced m-iodobenzoic acid are effectively recovered from the resin by acidification with hydrochloric acid.
Keywords
- Alkenes, Alkynes, Hypervalent iodine, Iodination, m-Iodosobenzoic acid, Scavenger
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Organic Chemistry
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In: Tetrahedron Letters, Vol. 49, No. 9, 08.01.2008, p. 1506-1509.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - m-Iodosylbenzoic acid, a tagged hypervalent iodine reagent for the iodo-functionalization of alkenes and alkynes
AU - Yusubov, Mekhman S.
AU - Yusubova, Roza Ya
AU - Kirschning, Andreas
AU - Park, Joo Yeon
AU - Chi, Ki Whan
N1 - Funding information: This work was funded by the Fonds der Chemischen Industrie. In addition, K.W.C., M.S.Y. and R.Y.Y. are grateful for the support of Brain Korea 21 program in Korea.
PY - 2008/1/8
Y1 - 2008/1/8
N2 - An efficient and facile method for the iodo-functionalization of alkenes 5 and alkynes 6 by using recyclable m-iodosylbenzoic acid (2) was developed. The final products can be easily isolated without any chromatographic purification by simple treatment of the crude mixture with an anionic exchange resin. Unreacted m-iodosylbenzoic acid and reduced m-iodobenzoic acid are effectively recovered from the resin by acidification with hydrochloric acid.
AB - An efficient and facile method for the iodo-functionalization of alkenes 5 and alkynes 6 by using recyclable m-iodosylbenzoic acid (2) was developed. The final products can be easily isolated without any chromatographic purification by simple treatment of the crude mixture with an anionic exchange resin. Unreacted m-iodosylbenzoic acid and reduced m-iodobenzoic acid are effectively recovered from the resin by acidification with hydrochloric acid.
KW - Alkenes
KW - Alkynes
KW - Hypervalent iodine
KW - Iodination
KW - m-Iodosobenzoic acid
KW - Scavenger
UR - http://www.scopus.com/inward/record.url?scp=38749083005&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2007.12.120
DO - 10.1016/j.tetlet.2007.12.120
M3 - Article
AN - SCOPUS:38749083005
VL - 49
SP - 1506
EP - 1509
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 9
ER -