Details
| Original language | English |
|---|---|
| Pages (from-to) | 355-380 |
| Number of pages | 26 |
| Journal | Advances in Biochemical Engineering/Biotechnology |
| Volume | 179 |
| Early online date | 26 Jan 2021 |
| Publication status | Published - 2022 |
Abstract
The emerging technique of microfluidics offers new approaches for precisely controlling fluidic conditions on a small scale, while simultaneously facilitating data collection in both high-throughput and quantitative manners. As such, the so-called lab-on-a-chip (LOC) systems have the potential to revolutionize the field of biotechnology. But what needs to happen in order to truly integrate them into routine biotechnological applications? In this chapter, some of the most promising applications of microfluidic technology within the field of biotechnology are surveyed, and a few strategies for overcoming current challenges posed by microfluidic LOC systems are examined. In addition, we also discuss the intensifying trend (across all biotechnology fields) of using point-of-use applications which is being facilitated by new technological achievements.
Keywords
- Biochemical engineering, Industrial biotechnology, Lab-on-a-chip, Medical biotechnology, Microfluidic screening, Microfluidics, Nanofluidics, Organ-on-a-chip, Point-of-care, Point-of-use
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Immunology and Microbiology(all)
- Applied Microbiology and Biotechnology
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In: Advances in Biochemical Engineering/Biotechnology, Vol. 179, 2022, p. 355-380.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Microfluidics in Biotechnology
T2 - Quo Vadis
AU - Winkler, Steffen
AU - Grünberger, Alexander
AU - Bahnemann, Janina
N1 - Funding Information: The authors would like to thank Niklas M. Epping (Institute of Technical Chemistry, Leibniz University Hannover, Germany) and Dr. Natalie Rotermund (Institute of Zoology, University of Hamburg, Germany) for their contribution in creating the illustrations.
PY - 2022
Y1 - 2022
N2 - The emerging technique of microfluidics offers new approaches for precisely controlling fluidic conditions on a small scale, while simultaneously facilitating data collection in both high-throughput and quantitative manners. As such, the so-called lab-on-a-chip (LOC) systems have the potential to revolutionize the field of biotechnology. But what needs to happen in order to truly integrate them into routine biotechnological applications? In this chapter, some of the most promising applications of microfluidic technology within the field of biotechnology are surveyed, and a few strategies for overcoming current challenges posed by microfluidic LOC systems are examined. In addition, we also discuss the intensifying trend (across all biotechnology fields) of using point-of-use applications which is being facilitated by new technological achievements.
AB - The emerging technique of microfluidics offers new approaches for precisely controlling fluidic conditions on a small scale, while simultaneously facilitating data collection in both high-throughput and quantitative manners. As such, the so-called lab-on-a-chip (LOC) systems have the potential to revolutionize the field of biotechnology. But what needs to happen in order to truly integrate them into routine biotechnological applications? In this chapter, some of the most promising applications of microfluidic technology within the field of biotechnology are surveyed, and a few strategies for overcoming current challenges posed by microfluidic LOC systems are examined. In addition, we also discuss the intensifying trend (across all biotechnology fields) of using point-of-use applications which is being facilitated by new technological achievements.
KW - Biochemical engineering
KW - Industrial biotechnology
KW - Lab-on-a-chip
KW - Medical biotechnology
KW - Microfluidic screening
KW - Microfluidics
KW - Nanofluidics
KW - Organ-on-a-chip
KW - Point-of-care
KW - Point-of-use
UR - http://www.scopus.com/inward/record.url?scp=85135370351&partnerID=8YFLogxK
U2 - 10.1007/10_2020_162
DO - 10.1007/10_2020_162
M3 - Article
C2 - 33495924
VL - 179
SP - 355
EP - 380
JO - Advances in Biochemical Engineering/Biotechnology
JF - Advances in Biochemical Engineering/Biotechnology
SN - 0724-6145
ER -