Details
| Original language | English |
|---|---|
| Pages (from-to) | 525-527 |
| Number of pages | 3 |
| Journal | Synlett |
| Issue number | 3 |
| Publication status | Published - 2002 |
Abstract
Aldehydes are homologated to the corresponding α-hydroxy methyl esters using lithiated dimethoxymethyl diphenyl phosphine oxide. The primary addition product of this Horner-Wittig process collapses to the corresponding α-hydroxy ester under proton-catalyzed conditions.
Keywords
- Aldehydes, Amino aldehydes, Carbanions, Hydrolyses, Wittig reactions
ASJC Scopus subject areas
- Chemistry(all)
- Organic Chemistry
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In: Synlett, No. 3, 2002, p. 525-527.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Lithiated dimethoxymethyl diphenyl phosphine oxide, a versatile formiate carbanion equivalent
AU - Monenschein, Holger
AU - Brünjes, Marco
AU - Kirschning, Andreas
PY - 2002
Y1 - 2002
N2 - Aldehydes are homologated to the corresponding α-hydroxy methyl esters using lithiated dimethoxymethyl diphenyl phosphine oxide. The primary addition product of this Horner-Wittig process collapses to the corresponding α-hydroxy ester under proton-catalyzed conditions.
AB - Aldehydes are homologated to the corresponding α-hydroxy methyl esters using lithiated dimethoxymethyl diphenyl phosphine oxide. The primary addition product of this Horner-Wittig process collapses to the corresponding α-hydroxy ester under proton-catalyzed conditions.
KW - Aldehydes
KW - Amino aldehydes
KW - Carbanions
KW - Hydrolyses
KW - Wittig reactions
UR - http://www.scopus.com/inward/record.url?scp=0036186009&partnerID=8YFLogxK
U2 - 10.1055/s-2002-20486
DO - 10.1055/s-2002-20486
M3 - Article
AN - SCOPUS:0036186009
SP - 525
EP - 527
JO - Synlett
JF - Synlett
SN - 0936-5214
IS - 3
ER -