Details
| Original language | English |
|---|---|
| Title of host publication | International Symposium on High Power Laser Ablation 2012 |
| Pages | 532-546 |
| Number of pages | 15 |
| Publication status | Published - 31 Jul 2012 |
| Externally published | Yes |
| Event | 9th International Symposium on High Power Laser Ablation 2012, HPLA 2012 - Santa Fe, NM, United States Duration: 30 Apr 2012 → 3 May 2012 |
Publication series
| Name | AIP Conference Proceedings |
|---|---|
| Volume | 1464 |
| ISSN (Print) | 0094-243X |
| ISSN (electronic) | 1551-7616 |
Abstract
Lasers are increasingly used to generate functional implants. This includes surface structuring to promote or avoid cell adhesion, laser sintering of metals to yield specific mechanical strength and resilience, and laser-generation of microstructured scaffolds. In this study, two further laser-based techniques for fabrication of multifunctional materials and implants are presented. First, a laser-based method for printing living cells is described. This technique allows to cover implant surfaces with a patient-identic biological footprint or to generate tissue constructs with or without scaffolds. Second, a novel laser-based technique is presented for controlled synthesis of multifunctionalized nanoparticles and nanoparticle-embedded composite implants. It is shown that beside cell-targeting, additional functions can be rigorously combined on a nanoparticle surface allowing complex cellular manipulations. Finally, using as a model implant a thermoplastic catheter, embedded nanoparticles reveal antibacterial and cellular proliferative behaviors by changing the nature of composite materials, opening new strategies for laser-generated implants.
Keywords
- Cell Printing, Laser Printing, Nanoparticles, Tissue Engineering
ASJC Scopus subject areas
- Physics and Astronomy(all)
- General Physics and Astronomy
Cite this
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International Symposium on High Power Laser Ablation 2012. 2012. p. 532-546 (AIP Conference Proceedings; Vol. 1464).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Laser-Based Micro- and Nanofabrication for Applications in Biomedicine
AU - Koch, L.
AU - Sajti, L.
AU - Schwenke, A.
AU - Klein, S.
AU - Unger, C.
AU - Gruene, M.
AU - Deiwick, A.
AU - Schlie, S.
AU - Chichkov, B.
PY - 2012/7/31
Y1 - 2012/7/31
N2 - Lasers are increasingly used to generate functional implants. This includes surface structuring to promote or avoid cell adhesion, laser sintering of metals to yield specific mechanical strength and resilience, and laser-generation of microstructured scaffolds. In this study, two further laser-based techniques for fabrication of multifunctional materials and implants are presented. First, a laser-based method for printing living cells is described. This technique allows to cover implant surfaces with a patient-identic biological footprint or to generate tissue constructs with or without scaffolds. Second, a novel laser-based technique is presented for controlled synthesis of multifunctionalized nanoparticles and nanoparticle-embedded composite implants. It is shown that beside cell-targeting, additional functions can be rigorously combined on a nanoparticle surface allowing complex cellular manipulations. Finally, using as a model implant a thermoplastic catheter, embedded nanoparticles reveal antibacterial and cellular proliferative behaviors by changing the nature of composite materials, opening new strategies for laser-generated implants.
AB - Lasers are increasingly used to generate functional implants. This includes surface structuring to promote or avoid cell adhesion, laser sintering of metals to yield specific mechanical strength and resilience, and laser-generation of microstructured scaffolds. In this study, two further laser-based techniques for fabrication of multifunctional materials and implants are presented. First, a laser-based method for printing living cells is described. This technique allows to cover implant surfaces with a patient-identic biological footprint or to generate tissue constructs with or without scaffolds. Second, a novel laser-based technique is presented for controlled synthesis of multifunctionalized nanoparticles and nanoparticle-embedded composite implants. It is shown that beside cell-targeting, additional functions can be rigorously combined on a nanoparticle surface allowing complex cellular manipulations. Finally, using as a model implant a thermoplastic catheter, embedded nanoparticles reveal antibacterial and cellular proliferative behaviors by changing the nature of composite materials, opening new strategies for laser-generated implants.
KW - Cell Printing
KW - Laser Printing
KW - Nanoparticles
KW - Tissue Engineering
UR - http://www.scopus.com/inward/record.url?scp=84873250636&partnerID=8YFLogxK
U2 - 10.1063/1.4739907
DO - 10.1063/1.4739907
M3 - Conference contribution
AN - SCOPUS:84873250636
SN - 9780735410688
T3 - AIP Conference Proceedings
SP - 532
EP - 546
BT - International Symposium on High Power Laser Ablation 2012
T2 - 9th International Symposium on High Power Laser Ablation 2012, HPLA 2012
Y2 - 30 April 2012 through 3 May 2012
ER -