Details
Original language | English |
---|---|
Pages (from-to) | 3891-3894 |
Number of pages | 4 |
Journal | Asian Journal of Chemistry |
Volume | 27 |
Issue number | 10 |
Publication status | Published - 1 Oct 2015 |
Externally published | Yes |
Abstract
Two new chalcone derivatives mallotoate A and mallotoate B were isolated from ethyl acetate fraction of Mallotus philippensis muell. Structure elucidation and the assignment of the isolates were achieved with the help of extensive 1D and 2D NMR studies. These compounds were identified using chemical and spectral data, as mallotoate A and mallotoate B, respectively. Both the compounds (mallotoate A and mallotoate B) showed significant fungicidal activity against Cladosporium cladosporioides in TLC bio-autography method. Using the same method, both mallotoate A and mallotoate B were tested for their antioxidant activities in DPPH radical scavenging activity in which, mallotoate B showed maximum and competitive activity (91.43 ± 0.82 %) against control drugs.
Keywords
- Antifungal activity, Antioxidant activity, Mallotoate A, Mallotoate B, Mallotus philippensis
ASJC Scopus subject areas
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In: Asian Journal of Chemistry, Vol. 27, No. 10, 01.10.2015, p. 3891-3894.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Isolation of two new mallotoates with antifungal and radical scavenging activities from Mallotus phillipensis muell
AU - Afzal, Masood
AU - Zhang, Liqun
AU - Cox, Russell J.
AU - Muhammad, Nawshad
AU - Khan, Shafiullah
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Two new chalcone derivatives mallotoate A and mallotoate B were isolated from ethyl acetate fraction of Mallotus philippensis muell. Structure elucidation and the assignment of the isolates were achieved with the help of extensive 1D and 2D NMR studies. These compounds were identified using chemical and spectral data, as mallotoate A and mallotoate B, respectively. Both the compounds (mallotoate A and mallotoate B) showed significant fungicidal activity against Cladosporium cladosporioides in TLC bio-autography method. Using the same method, both mallotoate A and mallotoate B were tested for their antioxidant activities in DPPH radical scavenging activity in which, mallotoate B showed maximum and competitive activity (91.43 ± 0.82 %) against control drugs.
AB - Two new chalcone derivatives mallotoate A and mallotoate B were isolated from ethyl acetate fraction of Mallotus philippensis muell. Structure elucidation and the assignment of the isolates were achieved with the help of extensive 1D and 2D NMR studies. These compounds were identified using chemical and spectral data, as mallotoate A and mallotoate B, respectively. Both the compounds (mallotoate A and mallotoate B) showed significant fungicidal activity against Cladosporium cladosporioides in TLC bio-autography method. Using the same method, both mallotoate A and mallotoate B were tested for their antioxidant activities in DPPH radical scavenging activity in which, mallotoate B showed maximum and competitive activity (91.43 ± 0.82 %) against control drugs.
KW - Antifungal activity
KW - Antioxidant activity
KW - Mallotoate A
KW - Mallotoate B
KW - Mallotus philippensis
UR - http://www.scopus.com/inward/record.url?scp=84950336703&partnerID=8YFLogxK
U2 - 10.14233/ajchem.2015.19047
DO - 10.14233/ajchem.2015.19047
M3 - Article
AN - SCOPUS:84950336703
VL - 27
SP - 3891
EP - 3894
JO - Asian Journal of Chemistry
JF - Asian Journal of Chemistry
SN - 0970-7077
IS - 10
ER -