Details
| Original language | English |
|---|---|
| Article number | 12 |
| Journal | Biomedical engineering online |
| Volume | 11 |
| Publication status | Published - 13 Mar 2012 |
Abstract
Background: In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery.Methods: ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD.Results: The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates.Conclusions: The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior.
Keywords
- Corrosion, In vitro study, Magnesium alloy, Plates
ASJC Scopus subject areas
- Health Professions(all)
- Radiological and Ultrasound Technology
- Materials Science(all)
- Biomaterials
- Engineering(all)
- Biomedical Engineering
- Medicine(all)
- Radiology Nuclear Medicine and imaging
Cite this
- Standard
- Harvard
- Apa
- Vancouver
- BibTeX
- RIS
In: Biomedical engineering online, Vol. 11, 12, 13.03.2012.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - In vitro corrosion of ZEK100 plates in Hank's Balanced Salt Solution
AU - Waizy, Hazibullah
AU - Weizbauer, Andreas
AU - Modrejewski, Christian
AU - Witte, Frank
AU - Windhagen, Henning
AU - Lucas, Arne
AU - Kieke, Marc
AU - Denkena, Berend
AU - Behrens, Peter
AU - Meyer-Lindenberg, Andrea
AU - Bach, Friedrich Wilhelm
AU - Thorey, Fritz
N1 - Funding information: The authors gratefully acknowledge the financial support given by German research society (DFG) within the collaborative research project (SFB 599). We thank Markus Badenhop for excellent technical support. We thank Christopher Müller for the design of Figure 1 and Hendrik Wardenga for creating Figure 2.
PY - 2012/3/13
Y1 - 2012/3/13
N2 - Background: In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery.Methods: ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD.Results: The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates.Conclusions: The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior.
AB - Background: In recent years magnesium alloys have been intensively investigated as potential resorbable materials with appropriate mechanical and corrosion properties. Particularly in orthopedic research magnesium is interesting because of its mechanical properties close to those of natural bone, the prevention of both stress shielding and removal of the implant after surgery.Methods: ZEK100 plates were examined in this in vitro study with Hank's Balanced Salt Solution under physiological conditions with a constant laminar flow rate. After 14, 28 and 42 days of immersion the ZEK100 plates were mechanically tested via four point bending test. The surfaces of the immersed specimens were characterized by SEM, EDX and XRD.Results: The four point bending test displayed an increased bending strength after 6 weeks immersion compared to the 2 week group and 4 week group. The characterization of the surface revealed the presence of high amounts of O, P and Ca on the surface and small Mg content. This indicates the precipitation of calcium phosphates with low solubility on the surface of the ZEK100 plates.Conclusions: The results of the present in vitro study indicate that ZEK100 is a potential candidate for degradable orthopedic implants. Further investigations are needed to examine the degradation behavior.
KW - Corrosion
KW - In vitro study
KW - Magnesium alloy
KW - Plates
UR - http://www.scopus.com/inward/record.url?scp=84857943420&partnerID=8YFLogxK
U2 - 10.1186/1475-925X-11-12
DO - 10.1186/1475-925X-11-12
M3 - Article
C2 - 22413949
AN - SCOPUS:84857943420
VL - 11
JO - Biomedical engineering online
JF - Biomedical engineering online
SN - 1475-925X
M1 - 12
ER -