Details
| Original language | English |
|---|---|
| Pages (from-to) | 837-840 |
| Number of pages | 4 |
| Journal | Chemical Engineering and Technology |
| Volume | 34 |
| Issue number | 5 |
| Publication status | Published - 4 Apr 2011 |
Abstract
In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.
Keywords
- Enzyme catalysis, Image processing, In situ microscopy, Process monitoring
ASJC Scopus subject areas
- Chemistry(all)
- General Chemistry
- Chemical Engineering(all)
- General Chemical Engineering
- Engineering(all)
- Industrial and Manufacturing Engineering
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In: Chemical Engineering and Technology, Vol. 34, No. 5, 04.04.2011, p. 837-840.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - In Situ Microscopy for Online Monitoring of Enzymatic Processes
AU - Prediger, A.
AU - Bluma, A.
AU - Höpfner, T.
AU - Lindner, P.
AU - Beutel, S.
AU - Scheper, T.
AU - Müller, J.
AU - Hilterhaus, L.
AU - Liese, A.
PY - 2011/4/4
Y1 - 2011/4/4
N2 - In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.
AB - In situ Microscopy (ISM) is an optical analysis method that allows non-invasive monitoring of processes in real-time. In this article online monitoring of enzyme carriers and the determination of their mechanical stability are presented as new application areas for ISM. As proof of principle the fragmentation of Lewatit VP OC 1600 particles in a stirred tank reactor is tracked. The image algorithm that was used to analyze the acquired image data is described and the results of the stability study are shown. Additional application possibilities of ISM in the area of two-phase systems are demonstrated. In situ microscopy (ISM) is an optical analysis method that allows noninvasive acquisition of image information from running processes. It is demonstrated how this analysis technique can be used to determine the mechanical stability of enzyme carriers. Furthermore, application possibilities of ISM for the characterization of two-phase systems are presented.
KW - Enzyme catalysis
KW - Image processing
KW - In situ microscopy
KW - Process monitoring
UR - http://www.scopus.com/inward/record.url?scp=79955028015&partnerID=8YFLogxK
U2 - 10.1002/ceat.201000563
DO - 10.1002/ceat.201000563
M3 - Article
AN - SCOPUS:79955028015
VL - 34
SP - 837
EP - 840
JO - Chemical Engineering and Technology
JF - Chemical Engineering and Technology
SN - 0930-7516
IS - 5
ER -