Improved polarimetric analysis of human skin through stitching: advantages, limitations, and applications in dermatology

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Original languageEnglish
Article number015007
Number of pages22
JournalBiomedical Physics and Engineering Express
Volume10
Issue number1
Publication statusPublished - 30 Nov 2023

Abstract

Polarimetry is a powerful tool for the analysis of the optical properties of materials and systems, such as human skin. However, in many polarimetric setups, the field of view is limited to a few square centimeters. In these cases, it is possible to resort to stitching techniques, which involve combining multiple Mueller matrix measurements obtained from different overlapping regions of the sample. In this paper, we propose a stitching technique for polarimetric data and discuss its advantages and limitations. We also describe the potential of image stitching for improving the accuracy and robustness of in vivo polarimetry in the presence of random patient movement. We conducted our research using a diverse set of samples which included porcine skin, human skin from arms and fingers, cold cuts of chicken and gelatine, alongside synthetically created sample data. Our results demonstrate the effectiveness of this technique for the application in dermatology. Each additional in vivo measurement enhances the field of view by approximately one third, thereby considerably augmenting the total observation area. We show that stitching enables for the polarimetric assessment of large skin patches which is useful for the diagnosis of inflammatory skin diseases.

Keywords

    dermatology, imaging, melanoma, polarimetry, skin diseases, stitching

ASJC Scopus subject areas

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Improved polarimetric analysis of human skin through stitching: advantages, limitations, and applications in dermatology. / Jütte, Lennart; Patel, Harshkumar; Roth, Bernhard.
In: Biomedical Physics and Engineering Express, Vol. 10, No. 1, 015007, 30.11.2023.

Research output: Contribution to journalArticleResearchpeer review

Jütte L, Patel H, Roth B. Improved polarimetric analysis of human skin through stitching: advantages, limitations, and applications in dermatology. Biomedical Physics and Engineering Express. 2023 Nov 30;10(1):015007. doi: 10.1088/2057-1976/ad0e87
Jütte, Lennart ; Patel, Harshkumar ; Roth, Bernhard. / Improved polarimetric analysis of human skin through stitching : advantages, limitations, and applications in dermatology. In: Biomedical Physics and Engineering Express. 2023 ; Vol. 10, No. 1.
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abstract = "Polarimetry is a powerful tool for the analysis of the optical properties of materials and systems, such as human skin. However, in many polarimetric setups, the field of view is limited to a few square centimeters. In these cases, it is possible to resort to stitching techniques, which involve combining multiple Mueller matrix measurements obtained from different overlapping regions of the sample. In this paper, we propose a stitching technique for polarimetric data and discuss its advantages and limitations. We also describe the potential of image stitching for improving the accuracy and robustness of in vivo polarimetry in the presence of random patient movement. We conducted our research using a diverse set of samples which included porcine skin, human skin from arms and fingers, cold cuts of chicken and gelatine, alongside synthetically created sample data. Our results demonstrate the effectiveness of this technique for the application in dermatology. Each additional in vivo measurement enhances the field of view by approximately one third, thereby considerably augmenting the total observation area. We show that stitching enables for the polarimetric assessment of large skin patches which is useful for the diagnosis of inflammatory skin diseases.",
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