Details
| Original language | English |
|---|---|
| Title of host publication | Advances in Biochemical Engineering/Biotechnology |
| Place of Publication | Cham |
| Pages | 17-41 |
| Number of pages | 25 |
| ISBN (electronic) | 978-3-030-54061-6 |
| Publication status | Published - 24 Apr 2020 |
Publication series
| Name | Advances in Biochemical Engineering/Biotechnology |
|---|---|
| Volume | 174 |
| ISSN (Print) | 0724-6145 |
| ISSN (electronic) | 1616-8542 |
Abstract
Aptamers are a specific class of ligands with high affinities comparable to antibodies, which are selected and synthesized in vitro. In combination with impedance spectroscopy as sensitive measurement method, we gain a class of biosensors with high potential for handheld devices and point-of-care tests. In this review, we report on recent advances in aptamer-based impedimetric biosensors. Besides giving a short summary of electrochemical measurement techniques, the most exciting innovative developments of detection strategies in the last decades are reviewed. Finally, important criteria for the comparison of aptamer-based biosensors are discussed.
Keywords
- Aptamer, Aptasensor, Biosensor, Capacitive, DNA origami, Electrode, Faradaic, Impedance, Label-free, Nanocomposites, Nanotechnology, Non-faradaic, Rapid detection, Redox mediator
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Immunology and Microbiology(all)
- Applied Microbiology and Biotechnology
Cite this
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Advances in Biochemical Engineering/Biotechnology. Cham, 2020. p. 17-41 (Advances in Biochemical Engineering/Biotechnology; Vol. 174).
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Impedimetric aptamer-based biosensors
T2 - Principles and techniques
AU - Reich, Peggy
AU - Preuß, John Alexander
AU - Bahner, Nicole
AU - Bahnemann, Janina
PY - 2020/4/24
Y1 - 2020/4/24
N2 - Aptamers are a specific class of ligands with high affinities comparable to antibodies, which are selected and synthesized in vitro. In combination with impedance spectroscopy as sensitive measurement method, we gain a class of biosensors with high potential for handheld devices and point-of-care tests. In this review, we report on recent advances in aptamer-based impedimetric biosensors. Besides giving a short summary of electrochemical measurement techniques, the most exciting innovative developments of detection strategies in the last decades are reviewed. Finally, important criteria for the comparison of aptamer-based biosensors are discussed.
AB - Aptamers are a specific class of ligands with high affinities comparable to antibodies, which are selected and synthesized in vitro. In combination with impedance spectroscopy as sensitive measurement method, we gain a class of biosensors with high potential for handheld devices and point-of-care tests. In this review, we report on recent advances in aptamer-based impedimetric biosensors. Besides giving a short summary of electrochemical measurement techniques, the most exciting innovative developments of detection strategies in the last decades are reviewed. Finally, important criteria for the comparison of aptamer-based biosensors are discussed.
KW - Aptamer
KW - Aptasensor
KW - Biosensor
KW - Capacitive
KW - DNA origami
KW - Electrode
KW - Faradaic
KW - Impedance
KW - Label-free
KW - Nanocomposites
KW - Nanotechnology
KW - Non-faradaic
KW - Rapid detection
KW - Redox mediator
UR - http://www.scopus.com/inward/record.url?scp=85089126129&partnerID=8YFLogxK
U2 - 10.1007/10_2019_113
DO - 10.1007/10_2019_113
M3 - Contribution to book/anthology
C2 - 32328684
AN - SCOPUS:85089126129
SN - 978-3-030-54060-9
T3 - Advances in Biochemical Engineering/Biotechnology
SP - 17
EP - 41
BT - Advances in Biochemical Engineering/Biotechnology
CY - Cham
ER -