Details
| Original language | English |
|---|---|
| Pages (from-to) | 222-229 |
| Number of pages | 8 |
| Journal | Exercise and Sport Sciences Reviews |
| Volume | 50 |
| Issue number | 4 |
| Publication status | Published - Oct 2022 |
Abstract
Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.
Keywords
- Exercise intolerance, Heart failure with reduced ejection fraction, Left ventricular assist device, Maximal oxygen uptake, Oxygen cascade
ASJC Scopus subject areas
- Medicine(all)
- Orthopedics and Sports Medicine
- Health Professions(all)
- Physical Therapy, Sports Therapy and Rehabilitation
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In: Exercise and Sport Sciences Reviews, Vol. 50, No. 4, 10.2022, p. 222-229.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure
AU - Huang, Janice
AU - McDonnell, Barry J.
AU - Lawley, Justin S.
AU - Byrd, Jessica
AU - Stöhr, Eric J.
AU - Cornwell, William K.
N1 - Funding Information: Dr. Cornwell reports funding from the National Institutes of Health and Medtronic Corp.
PY - 2022/10
Y1 - 2022/10
N2 - Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.
AB - Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.
KW - Exercise intolerance
KW - Heart failure with reduced ejection fraction
KW - Left ventricular assist device
KW - Maximal oxygen uptake
KW - Oxygen cascade
UR - http://www.scopus.com/inward/record.url?scp=85137661947&partnerID=8YFLogxK
U2 - 10.1249/jes.0000000000000303
DO - 10.1249/jes.0000000000000303
M3 - Article
C2 - 36095073
AN - SCOPUS:85137661947
VL - 50
SP - 222
EP - 229
JO - Exercise and Sport Sciences Reviews
JF - Exercise and Sport Sciences Reviews
SN - 0091-6331
IS - 4
ER -