Details
| Original language | English |
|---|---|
| Title of host publication | 2023 IEEE SENSORS, SENSORS 2023 - Conference Proceedings |
| Publisher | Institute of Electrical and Electronics Engineers Inc. |
| ISBN (electronic) | 9798350303872 |
| Publication status | Published - 2023 |
| Event | 2023 IEEE SENSORS - Vienna, Austria Duration: 29 Oct 2023 → 1 Nov 2023 |
Publication series
| Name | Proceedings of IEEE Sensors |
|---|---|
| ISSN (Print) | 1930-0395 |
| ISSN (electronic) | 2168-9229 |
Abstract
Ion mobility spectrometry (IMS) is a well-known technique for the detection of chemical warfare agents, other highly toxic compounds, drugs of abuse and explosives, since IMS have low detection limits in the pptV-range, short response times of just few seconds, decent resolving power and compact size suitable for onsite, hand-held and even drone applications. However, depending on the ionization source and the resolving power, some compounds are difficult to detect due to chemical interferences during ionization or overlapping peaks in the ion mobility spectrum. Here, we present a promising approach, High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), for fast and reliable detection of hazardous compounds, which is based on IMS but operated at low pressure leading to less chemical interferences including humidity during ionization, a controlled reactant ion population and a broader spectrum of detectable compounds. Furthermore, by varying the drift field strength up to 120 Td overlapping peaks in the spectrum and thus false positives can be resolved by the field-dependent ion mobility as an additional separation dimension or by analyzing ion specific fragments generated through collision induced fragmentation at higher field strengths.
Keywords
- chemical warfare agents, CWA, High Kinetic Energy Ion Mobility Spectrometry, HiKE-IMS, IMS, Ion mobility spectrometry
ASJC Scopus subject areas
- Engineering(all)
- Electrical and Electronic Engineering
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2023 IEEE SENSORS, SENSORS 2023 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2023. (Proceedings of IEEE Sensors).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - High Kinetic Energy Ion Mobility Spectrometry
T2 - 2023 IEEE SENSORS
AU - Schaefer, Christoph
AU - Schlottmann, Florian
AU - Zimmermann, Stefan
PY - 2023
Y1 - 2023
N2 - Ion mobility spectrometry (IMS) is a well-known technique for the detection of chemical warfare agents, other highly toxic compounds, drugs of abuse and explosives, since IMS have low detection limits in the pptV-range, short response times of just few seconds, decent resolving power and compact size suitable for onsite, hand-held and even drone applications. However, depending on the ionization source and the resolving power, some compounds are difficult to detect due to chemical interferences during ionization or overlapping peaks in the ion mobility spectrum. Here, we present a promising approach, High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), for fast and reliable detection of hazardous compounds, which is based on IMS but operated at low pressure leading to less chemical interferences including humidity during ionization, a controlled reactant ion population and a broader spectrum of detectable compounds. Furthermore, by varying the drift field strength up to 120 Td overlapping peaks in the spectrum and thus false positives can be resolved by the field-dependent ion mobility as an additional separation dimension or by analyzing ion specific fragments generated through collision induced fragmentation at higher field strengths.
AB - Ion mobility spectrometry (IMS) is a well-known technique for the detection of chemical warfare agents, other highly toxic compounds, drugs of abuse and explosives, since IMS have low detection limits in the pptV-range, short response times of just few seconds, decent resolving power and compact size suitable for onsite, hand-held and even drone applications. However, depending on the ionization source and the resolving power, some compounds are difficult to detect due to chemical interferences during ionization or overlapping peaks in the ion mobility spectrum. Here, we present a promising approach, High Kinetic Energy Ion Mobility Spectrometry (HiKE-IMS), for fast and reliable detection of hazardous compounds, which is based on IMS but operated at low pressure leading to less chemical interferences including humidity during ionization, a controlled reactant ion population and a broader spectrum of detectable compounds. Furthermore, by varying the drift field strength up to 120 Td overlapping peaks in the spectrum and thus false positives can be resolved by the field-dependent ion mobility as an additional separation dimension or by analyzing ion specific fragments generated through collision induced fragmentation at higher field strengths.
KW - chemical warfare agents
KW - CWA
KW - High Kinetic Energy Ion Mobility Spectrometry
KW - HiKE-IMS
KW - IMS
KW - Ion mobility spectrometry
UR - http://www.scopus.com/inward/record.url?scp=85179760824&partnerID=8YFLogxK
U2 - 10.1109/SENSORS56945.2023.10324855
DO - 10.1109/SENSORS56945.2023.10324855
M3 - Conference contribution
AN - SCOPUS:85179760824
T3 - Proceedings of IEEE Sensors
BT - 2023 IEEE SENSORS, SENSORS 2023 - Conference Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 29 October 2023 through 1 November 2023
ER -