Details
| Original language | English |
|---|---|
| Pages (from-to) | 1716-1721 |
| Number of pages | 6 |
| Journal | Chemistry - a European journal |
| Volume | 25 |
| Issue number | 7 |
| Publication status | Published - 1 Feb 2019 |
| Externally published | Yes |
Abstract
In cooperative catalysis, the combination of chemo- and biocatalysts to perform one-pot reactions is a powerful tool for the improvement of chemical synthesis. Herein, UiO-66-NH2 was employed to stepwise immobilize Pd nanoparticles (NPs) and Candida antarctica lipase B (CalB) for the fabrication of biohybrid catalysts for cascade reactions. Distinct from traditional materials, UiO-66-NH2 has a robust but tunable structure that can be utilized with a ligand exchange approach to adjust its hydrophobicity, resulting in excellent catalyst dispersity in diverse reaction media. These attractive properties contribute to the formation of MOF-based biohybrid catalysts with high activity and selectivity in the synthesis of benzyl hexanoate from benzaldehyde and ethyl hexanoate. With this proof-of-concept, we reasonably expect that future tailor-made MOFs can combine other catalysts, ranging from chemical to biological catalysts for applications in industry.
Keywords
- cascade reactions, enzyme immobilization, heterogeneous catalysis, metal–organic frameworks, Pd nanoparticles
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Chemistry(all)
- Organic Chemistry
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In: Chemistry - a European journal, Vol. 25, No. 7, 01.02.2019, p. 1716-1721.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Heterogeneous Metal–Organic-Framework-Based Biohybrid Catalysts for Cascade Reactions in Organic Solvent
AU - Wang, Yangxin
AU - Zhang, Ningning
AU - Zhang, En
AU - Han, Yunhu
AU - Qi, Zhenhui
AU - Ansorge-Schumacher, Marion B.
AU - Ge, Yan
AU - Wu, Changzhu
N1 - Funding Information: The Thousand Talents Program (1800-16GH030121), China Postdoctoral Science Foundation (2017M623231), Fundamental Research Funds for the Central Universities (3102018zy051), and DFG (WU 814/1-1) are acknowledged.
PY - 2019/2/1
Y1 - 2019/2/1
N2 - In cooperative catalysis, the combination of chemo- and biocatalysts to perform one-pot reactions is a powerful tool for the improvement of chemical synthesis. Herein, UiO-66-NH2 was employed to stepwise immobilize Pd nanoparticles (NPs) and Candida antarctica lipase B (CalB) for the fabrication of biohybrid catalysts for cascade reactions. Distinct from traditional materials, UiO-66-NH2 has a robust but tunable structure that can be utilized with a ligand exchange approach to adjust its hydrophobicity, resulting in excellent catalyst dispersity in diverse reaction media. These attractive properties contribute to the formation of MOF-based biohybrid catalysts with high activity and selectivity in the synthesis of benzyl hexanoate from benzaldehyde and ethyl hexanoate. With this proof-of-concept, we reasonably expect that future tailor-made MOFs can combine other catalysts, ranging from chemical to biological catalysts for applications in industry.
AB - In cooperative catalysis, the combination of chemo- and biocatalysts to perform one-pot reactions is a powerful tool for the improvement of chemical synthesis. Herein, UiO-66-NH2 was employed to stepwise immobilize Pd nanoparticles (NPs) and Candida antarctica lipase B (CalB) for the fabrication of biohybrid catalysts for cascade reactions. Distinct from traditional materials, UiO-66-NH2 has a robust but tunable structure that can be utilized with a ligand exchange approach to adjust its hydrophobicity, resulting in excellent catalyst dispersity in diverse reaction media. These attractive properties contribute to the formation of MOF-based biohybrid catalysts with high activity and selectivity in the synthesis of benzyl hexanoate from benzaldehyde and ethyl hexanoate. With this proof-of-concept, we reasonably expect that future tailor-made MOFs can combine other catalysts, ranging from chemical to biological catalysts for applications in industry.
KW - cascade reactions
KW - enzyme immobilization
KW - heterogeneous catalysis
KW - metal–organic frameworks
KW - Pd nanoparticles
UR - http://www.scopus.com/inward/record.url?scp=85059451830&partnerID=8YFLogxK
U2 - 10.1002/chem.201805680
DO - 10.1002/chem.201805680
M3 - Article
C2 - 30475411
AN - SCOPUS:85059451830
VL - 25
SP - 1716
EP - 1721
JO - Chemistry - a European journal
JF - Chemistry - a European journal
SN - 0947-6539
IS - 7
ER -