Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Authors

  • Sonja Johannsmeier
  • Patrick Heeger
  • Mitsuhiro Terakawa
  • Stefan Kalies
  • Alexander Heisterkamp
  • Tammo Ripken
  • Dag Heinemann

Research Organisations

External Research Organisations

  • Laser Zentrum Hannover e.V. (LZH)
  • NIFE - Lower Saxony Centre for Biomedical Engineering, Implant Research and Development
  • Cluster of Excellence Hearing4all
  • Keio University
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Details

Original languageEnglish
Title of host publicationMedical Laser Applications and Laser-Tissue Interactions VIII
EditorsRonald Sroka, Lothar D. Lilge
PublisherSPIE
ISBN (electronic)9781510612921
Publication statusPublished - 1 Aug 2017
EventMedical Laser Applications and Laser-Tissue Interactions VIII 2017 - Munich, Germany
Duration: 25 Jun 201729 Jun 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10417
ISSN (Print)1605-7422

Abstract

Gold nanoparticle mediated laser stimulation of neuronal cells allows for cell activation on a single-cell level. It could therefore be considered an alternative to classical electric neurostimulation. The physiological impact of this new approach has not been intensively studied so far. Here, we investigate the targeted cell's reaction to a laser stimulus based on its calcium response. A complex cellular reaction involving multiple sources has been revealed.

Keywords

    Gold nanoparticles, Laser-cell-interaction, Neuroimplants, Neurostimulation, Stress signaling

ASJC Scopus subject areas

Cite this

Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. / Johannsmeier, Sonja; Heeger, Patrick; Terakawa, Mitsuhiro et al.
Medical Laser Applications and Laser-Tissue Interactions VIII. ed. / Ronald Sroka; Lothar D. Lilge. SPIE, 2017. 104170B (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10417).

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Johannsmeier, S, Heeger, P, Terakawa, M, Kalies, S, Heisterkamp, A, Ripken, T & Heinemann, D 2017, Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. in R Sroka & LD Lilge (eds), Medical Laser Applications and Laser-Tissue Interactions VIII., 104170B, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10417, SPIE, Medical Laser Applications and Laser-Tissue Interactions VIII 2017, Munich, Germany, 25 Jun 2017. https://doi.org/10.1117/12.2284174
Johannsmeier, S., Heeger, P., Terakawa, M., Kalies, S., Heisterkamp, A., Ripken, T., & Heinemann, D. (2017). Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. In R. Sroka, & L. D. Lilge (Eds.), Medical Laser Applications and Laser-Tissue Interactions VIII Article 104170B (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10417). SPIE. https://doi.org/10.1117/12.2284174
Johannsmeier S, Heeger P, Terakawa M, Kalies S, Heisterkamp A, Ripken T et al. Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. In Sroka R, Lilge LD, editors, Medical Laser Applications and Laser-Tissue Interactions VIII. SPIE. 2017. 104170B. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2284174
Johannsmeier, Sonja ; Heeger, Patrick ; Terakawa, Mitsuhiro et al. / Gold nanoparticle-mediated laser stimulation causes a complex stress signal in neuronal cells. Medical Laser Applications and Laser-Tissue Interactions VIII. editor / Ronald Sroka ; Lothar D. Lilge. SPIE, 2017. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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