Gemeinsame Effektmaße in medizinischen und gesundheitsökonomischen Studien? Ergebnisse einer explorativen Ärztebefragung

Research output: Contribution to journalArticleResearchpeer review

Authors

  • Hans Helmut König
  • Christiane Hoffmann
  • J. Matthias Graf Von Der Schulenburg
  • Reiner Leidl

External Research Organisations

  • Ulm University
View graph of relations

Details

Translated title of the contributionCommon effect measures in medical and economic studies? Results of an exploratory survey of physicians: Results of an exploratory survey of physicians
Original languageMultiple languages
Pages (from-to)665-672
Number of pages8
JournalMedizinische Klinik
Volume94
Issue number12
Publication statusPublished - Dec 1999

Abstract

Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.

ASJC Scopus subject areas

Cite this

Gemeinsame Effektmaße in medizinischen und gesundheitsökonomischen Studien? Ergebnisse einer explorativen Ärztebefragung. / König, Hans Helmut; Hoffmann, Christiane; Von Der Schulenburg, J. Matthias Graf et al.
In: Medizinische Klinik, Vol. 94, No. 12, 12.1999, p. 665-672.

Research output: Contribution to journalArticleResearchpeer review

König HH, Hoffmann C, Von Der Schulenburg JMG, Leidl R. Gemeinsame Effektmaße in medizinischen und gesundheitsökonomischen Studien? Ergebnisse einer explorativen Ärztebefragung. Medizinische Klinik. 1999 Dec;94(12):665-672. doi: 10.1007/bf03044756
König, Hans Helmut ; Hoffmann, Christiane ; Von Der Schulenburg, J. Matthias Graf et al. / Gemeinsame Effektmaße in medizinischen und gesundheitsökonomischen Studien? Ergebnisse einer explorativen Ärztebefragung. In: Medizinische Klinik. 1999 ; Vol. 94, No. 12. pp. 665-672.
Download
@article{89f4bed7f8f4471aa9ea6aeaee3d2581,
title = "Gemeinsame Effektma{\ss}e in medizinischen und gesundheits{\"o}konomischen Studien?: Ergebnisse einer explorativen {\"A}rztebefragung",
abstract = "Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.",
keywords = "Clinical and economic end-points, Cost-utility analysis, Economic evaluation, Health-related quality of life, Quality-adjusted life year (QALY)",
author = "K{\"o}nig, {Hans Helmut} and Christiane Hoffmann and {Von Der Schulenburg}, {J. Matthias Graf} and Reiner Leidl",
year = "1999",
month = dec,
doi = "10.1007/bf03044756",
language = "Multiple languages",
volume = "94",
pages = "665--672",
journal = "Medizinische Klinik",
issn = "0723-5003",
publisher = "Urban und Vogel",
number = "12",

}

Download

TY - JOUR

T1 - Gemeinsame Effektmaße in medizinischen und gesundheitsökonomischen Studien?

T2 - Ergebnisse einer explorativen Ärztebefragung

AU - König, Hans Helmut

AU - Hoffmann, Christiane

AU - Von Der Schulenburg, J. Matthias Graf

AU - Leidl, Reiner

PY - 1999/12

Y1 - 1999/12

N2 - Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.

AB - Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.

KW - Clinical and economic end-points

KW - Cost-utility analysis

KW - Economic evaluation

KW - Health-related quality of life

KW - Quality-adjusted life year (QALY)

UR - http://www.scopus.com/inward/record.url?scp=0343851698&partnerID=8YFLogxK

U2 - 10.1007/bf03044756

DO - 10.1007/bf03044756

M3 - Article

C2 - 10641508

AN - SCOPUS:0343851698

VL - 94

SP - 665

EP - 672

JO - Medizinische Klinik

JF - Medizinische Klinik

SN - 0723-5003

IS - 12

ER -