Details
| Translated title of the contribution | Common effect measures in medical and economic studies? Results of an exploratory survey of physicians: Results of an exploratory survey of physicians |
|---|---|
| Original language | Multiple languages |
| Pages (from-to) | 665-672 |
| Number of pages | 8 |
| Journal | Medizinische Klinik |
| Volume | 94 |
| Issue number | 12 |
| Publication status | Published - Dec 1999 |
Abstract
Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.
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In: Medizinische Klinik, Vol. 94, No. 12, 12.1999, p. 665-672.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Gemeinsame Effektmaße in medizinischen und gesundheitsökonomischen Studien?
T2 - Ergebnisse einer explorativen Ärztebefragung
AU - König, Hans Helmut
AU - Hoffmann, Christiane
AU - Von Der Schulenburg, J. Matthias Graf
AU - Leidl, Reiner
PY - 1999/12
Y1 - 1999/12
N2 - Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.
AB - Background: In economic evaluation studies quality-adjusted life years (QALYs) are often used as measure of effects. QALYs are calculated by weighing survival time with a valuation of health-related quality of life (HRQoL). The results may support clinical decisions for patient groups provided that physicians consider QALYs acceptable and clinically relevant. This study investigates whether physicians accept the various methodological steps of the calculation of QALYs and whether effect measures that result from these steps are useful in clinical studies, too. Methods: In summer 1998, 41 physicians (21 principal investigators of clinical studies in oncology, 12 surgeons, 8 primary care physicians) completed a questionnaire. Results: 90% of the physicians considered HRQoL a relevant measure of clinical effectiveness but only 54% were familiar with the concept of HRQoL. 80% accepted the creation of an index of HRQoL, 68% accepted the integration of HRQoL and survival time into a single effect measure, but only 44% accepted the multiplicative way of calculating QALYs. According to most physicians, HRQoL should be valued either by study patients or health care professionals rather than general population samples. 92% of the physicians considered identical effect measures in clinical and economic studies necessary or desirable. Conclusions: QALYs are not generally rejected by the responding physicians. The integration of HRQoL is largely accepted. The multiplicative way of combining survival time and HRQoL values is rejected by many physicians. The findings can be used to define a starting point for the development of common effect measures in medicine and health economics.
KW - Clinical and economic end-points
KW - Cost-utility analysis
KW - Economic evaluation
KW - Health-related quality of life
KW - Quality-adjusted life year (QALY)
UR - http://www.scopus.com/inward/record.url?scp=0343851698&partnerID=8YFLogxK
U2 - 10.1007/bf03044756
DO - 10.1007/bf03044756
M3 - Article
C2 - 10641508
AN - SCOPUS:0343851698
VL - 94
SP - 665
EP - 672
JO - Medizinische Klinik
JF - Medizinische Klinik
SN - 0723-5003
IS - 12
ER -