Details
| Original language | English |
|---|---|
| Title of host publication | Ophthalmic Technologies XV |
| Publisher | SPIE |
| Pages | 278-287 |
| Number of pages | 10 |
| Publication status | Published - 21 Jul 2005 |
| Event | SPIE BIOS - San Jose, CA, United States Duration: 22 Jan 2005 → 27 Jan 2005 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 5688 |
| ISSN (Print) | 1605-7422 |
Abstract
According to Helmholtz' theory of accommodation one of the mayor reasons for the development of presbyopia is the increasing sclerosis of the lens. One concept to delay the process of sclerosis or even regain the deformation ability of the lens might be the treatment of the lens by femtosecond laser pulses. Our aim was to evaluate appropriate laser parameters for this possible treatment and to analyse potential changes in deformation ability of the treated lenses. We performed different cutting patterns in enucleated pig lenses (ex vivo) using the disruptive effect of an ultrafast near-infrared laser induced optical breakdown. Pulse energies and spot separation of the laser pulses were varied to investigate the effect on the generated cut. For an evaluation of the gain in deformation ability the lenses were rotated before and after treatment and the changes in lens thickness due to centrifugal forces were measured. In result, a smooth cutting was possible with appropriate parameters. The experiments showed an increase of elasticity in 70% of the eyes. When the lenses were treated more statistically, an average deformation ability increase of nearly 20%, determined by the change of thickness between untreated and treated lens, was measured.
Keywords
- Accommodation, Age-related, Femtosecond Laser, Lens, Ophthalmology, Presbyopia, Ultrashort Laser Pulses
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Materials Science(all)
- Biomaterials
- Physics and Astronomy(all)
- Atomic and Molecular Physics, and Optics
- Medicine(all)
- Radiology Nuclear Medicine and imaging
Cite this
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Ophthalmic Technologies XV. SPIE, 2005. p. 278-287 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 5688).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Fs-laser induced elasticity changes to improve presbyopic lens accommodation
AU - Ripken, T.
AU - Oberheide, U.
AU - Ziltz, C.
AU - Ertmer, W.
AU - Gerten, G.
AU - Lubatschowski, H.
PY - 2005/7/21
Y1 - 2005/7/21
N2 - According to Helmholtz' theory of accommodation one of the mayor reasons for the development of presbyopia is the increasing sclerosis of the lens. One concept to delay the process of sclerosis or even regain the deformation ability of the lens might be the treatment of the lens by femtosecond laser pulses. Our aim was to evaluate appropriate laser parameters for this possible treatment and to analyse potential changes in deformation ability of the treated lenses. We performed different cutting patterns in enucleated pig lenses (ex vivo) using the disruptive effect of an ultrafast near-infrared laser induced optical breakdown. Pulse energies and spot separation of the laser pulses were varied to investigate the effect on the generated cut. For an evaluation of the gain in deformation ability the lenses were rotated before and after treatment and the changes in lens thickness due to centrifugal forces were measured. In result, a smooth cutting was possible with appropriate parameters. The experiments showed an increase of elasticity in 70% of the eyes. When the lenses were treated more statistically, an average deformation ability increase of nearly 20%, determined by the change of thickness between untreated and treated lens, was measured.
AB - According to Helmholtz' theory of accommodation one of the mayor reasons for the development of presbyopia is the increasing sclerosis of the lens. One concept to delay the process of sclerosis or even regain the deformation ability of the lens might be the treatment of the lens by femtosecond laser pulses. Our aim was to evaluate appropriate laser parameters for this possible treatment and to analyse potential changes in deformation ability of the treated lenses. We performed different cutting patterns in enucleated pig lenses (ex vivo) using the disruptive effect of an ultrafast near-infrared laser induced optical breakdown. Pulse energies and spot separation of the laser pulses were varied to investigate the effect on the generated cut. For an evaluation of the gain in deformation ability the lenses were rotated before and after treatment and the changes in lens thickness due to centrifugal forces were measured. In result, a smooth cutting was possible with appropriate parameters. The experiments showed an increase of elasticity in 70% of the eyes. When the lenses were treated more statistically, an average deformation ability increase of nearly 20%, determined by the change of thickness between untreated and treated lens, was measured.
KW - Accommodation
KW - Age-related
KW - Femtosecond Laser
KW - Lens
KW - Ophthalmology
KW - Presbyopia
KW - Ultrashort Laser Pulses
UR - http://www.scopus.com/inward/record.url?scp=21844475904&partnerID=8YFLogxK
U2 - 10.1117/12.588242
DO - 10.1117/12.588242
M3 - Conference contribution
AN - SCOPUS:21844475904
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
SP - 278
EP - 287
BT - Ophthalmic Technologies XV
PB - SPIE
T2 - SPIE BIOS
Y2 - 22 January 2005 through 27 January 2005
ER -