Focus stacking in non-contact dermoscopy

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Original languageEnglish
Article number065022
JournalBiomedical Physics and Engineering Express
Volume8
Issue number6
Publication statusPublished - Nov 2022

Abstract

Dermoscopy is the main tool for early detection of skin cancer. Non-contact dermoscopes often suffer from a small depth of field leading to images of skin topographies with regions that are not in focus. We aim to provide an easy-to-implement focus stacking-based approach to ensure all-in-focus images from a non-contact dermoscope. Further, we aim to extract additional information about the skin topography from the image stacks. The focus stacking procedure itself is implemented in a non-contact dermoscope with an electrically adjustable focus realized by using a tunable liquid lens. We show that all-in-focus imaging is possible for non-contact dermoscopy and deliver a method to extract topographical information for dermatologists from the acquired image stacks. Our finding indicate that the approach can be valuable for non-contact dermoscopic examination as well as for the early detection of skin diseases such as cancer as it possible to derive hyperfocus images and information on the skin topography. With this, we were able to develop a software for the acquisition of the raw image data and its processing into a high resolution hyperresolution dermoscopic image. In the next steps, we plan to apply the approach in the clinical environment for skin cancer diagnostics or imaging of inflammatory skin diseases.

Keywords

    dermatology, dermoscopy, focus stacking, melanoma, skin, skin cancer imaging

ASJC Scopus subject areas

Sustainable Development Goals

Cite this

Focus stacking in non-contact dermoscopy. / Jütte, Lennart; yang, zhiyao ; Sharma, Gaurav et al.
In: Biomedical Physics and Engineering Express, Vol. 8, No. 6, 065022, 11.2022.

Research output: Contribution to journalArticleResearchpeer review

Jütte, L, yang, Z, Sharma, G & Roth, B 2022, 'Focus stacking in non-contact dermoscopy', Biomedical Physics and Engineering Express, vol. 8, no. 6, 065022. https://doi.org/10.1088/2057-1976/ac9847
Jütte, L., yang, Z., Sharma, G., & Roth, B. (2022). Focus stacking in non-contact dermoscopy. Biomedical Physics and Engineering Express, 8(6), Article 065022. https://doi.org/10.1088/2057-1976/ac9847
Jütte L, yang Z, Sharma G, Roth B. Focus stacking in non-contact dermoscopy. Biomedical Physics and Engineering Express. 2022 Nov;8(6):065022. doi: 10.1088/2057-1976/ac9847
Jütte, Lennart ; yang, zhiyao ; Sharma, Gaurav et al. / Focus stacking in non-contact dermoscopy. In: Biomedical Physics and Engineering Express. 2022 ; Vol. 8, No. 6.
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abstract = "Dermoscopy is the main tool for early detection of skin cancer. Non-contact dermoscopes often suffer from a small depth of field leading to images of skin topographies with regions that are not in focus. We aim to provide an easy-to-implement focus stacking-based approach to ensure all-in-focus images from a non-contact dermoscope. Further, we aim to extract additional information about the skin topography from the image stacks. The focus stacking procedure itself is implemented in a non-contact dermoscope with an electrically adjustable focus realized by using a tunable liquid lens. We show that all-in-focus imaging is possible for non-contact dermoscopy and deliver a method to extract topographical information for dermatologists from the acquired image stacks. Our finding indicate that the approach can be valuable for non-contact dermoscopic examination as well as for the early detection of skin diseases such as cancer as it possible to derive hyperfocus images and information on the skin topography. With this, we were able to develop a software for the acquisition of the raw image data and its processing into a high resolution hyperresolution dermoscopic image. In the next steps, we plan to apply the approach in the clinical environment for skin cancer diagnostics or imaging of inflammatory skin diseases.",
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note = "Funding Information: This work has been supported by iToBoS (Intelligent Total Body Scanner for Early Detection of Melanoma), project funded by the European Union{\textquoteright}s Horizon 2020 research and innovation programme, under grant agreement No 965221. Also, financial support by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany{\textquoteright}s Excellence Strategy within the Cluster of Excellence PhoenixD (EXC 2122, Project ID 390833453) is acknowledged. ",
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