Details
| Original language | English |
|---|---|
| Pages (from-to) | 4081-4088 |
| Number of pages | 8 |
| Journal | Synthesis (Germany) |
| Volume | 50 |
| Issue number | 20 |
| Publication status | Published - 2018 |
Abstract
A simple and convenient synthesis of ω-iodoaliphatic carboxylic acids and esters by the reaction of cyclic ketones with iodine and hydrogen peroxide in the presence of catalytic CuCl has been developed. ω-Iodoaliphatic carboxylic esters were further used for the efficient preparation of di(2-pyridylmethylamino)alkanoic acids in excellent yields.
Keywords
- chelating reagents, cyclic ketones, di-(2-picolyl)amine, di-(2-pyridylmethylamino)alkanoic acids, ligands, ω-iodo-aliphatic carboxylic esters, ω-iodoaliphatic carboxylic acids
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Chemistry(all)
- Organic Chemistry
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In: Synthesis (Germany), Vol. 50, No. 20, 2018, p. 4081-4088.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Expedient synthesis of long-chain ω-substituted fatty acids and esters from cyclic ketones using iodine and hydrogen peroxide
AU - Podrezova, Ekaterina V.
AU - Larkina, Maria S.
AU - Belousov, Mikhail V.
AU - Kirschning, Andreas
AU - Zhdankin, Viktor V.
AU - Yusubov, Mekhman S.
PY - 2018
Y1 - 2018
N2 - A simple and convenient synthesis of ω-iodoaliphatic carboxylic acids and esters by the reaction of cyclic ketones with iodine and hydrogen peroxide in the presence of catalytic CuCl has been developed. ω-Iodoaliphatic carboxylic esters were further used for the efficient preparation of di(2-pyridylmethylamino)alkanoic acids in excellent yields.
AB - A simple and convenient synthesis of ω-iodoaliphatic carboxylic acids and esters by the reaction of cyclic ketones with iodine and hydrogen peroxide in the presence of catalytic CuCl has been developed. ω-Iodoaliphatic carboxylic esters were further used for the efficient preparation of di(2-pyridylmethylamino)alkanoic acids in excellent yields.
KW - chelating reagents
KW - cyclic ketones
KW - di-(2-picolyl)amine
KW - di-(2-pyridylmethylamino)alkanoic acids
KW - ligands
KW - ω-iodo-aliphatic carboxylic esters
KW - ω-iodoaliphatic carboxylic acids
UR - http://www.scopus.com/inward/record.url?scp=85054397855&partnerID=8YFLogxK
U2 - 10.1055/s-0036-1591598
DO - 10.1055/s-0036-1591598
M3 - Article
AN - SCOPUS:85054397855
VL - 50
SP - 4081
EP - 4088
JO - Synthesis (Germany)
JF - Synthesis (Germany)
SN - 0039-7881
IS - 20
ER -