Details
| Original language | English |
|---|---|
| Pages (from-to) | 2407-2420 |
| Number of pages | 14 |
| Journal | Nanophotonics |
| Volume | 10 |
| Issue number | 9 |
| Publication status | Published - 21 May 2021 |
Abstract
The optoelectronic properties of semiconductor nanoparticles make them valuable candidates for the long-term monitoring of transmembrane electric fields in excitable cells. In this work, we show that the electric field sensitivity of the fluorescence intensity of type-I and quasi-type-II quantum dots and quantum rods is enhanced under two-photon excitation compared to single-photon excitation. Based on the superior electric field sensitivity of the two-photon excited fluorescence, we demonstrate the ability of quantum dots and rods to track fast switching E-fields. These findings indicate the potential of semiconductor nanoparticles as cellular voltage probes in multiphoton imaging.
Keywords
- electric field, quantum dot/rod, semiconductor nanoparticle, two-photon fluorescence, voltage sensing
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Physics and Astronomy(all)
- Atomic and Molecular Physics, and Optics
- Engineering(all)
- Electrical and Electronic Engineering
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
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In: Nanophotonics, Vol. 10, No. 9, 21.05.2021, p. 2407-2420.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Enhanced electric field sensitivity of quantum dot/rod two-photon fluorescence and its relevance for cell transmembrane voltage imaging
AU - Jooken, S.
AU - De Coene, Y.
AU - Deschaume, O.
AU - Zámbó, D.
AU - Aubert, T.
AU - Hens, Z.
AU - Dorfs, D.
AU - Verbiest, T.
AU - Clays, K.
AU - Callewaert, G.
AU - Bartic, C.
N1 - Funding Information: Research funding: S. Jooken acknowledges the financial support by the Flanders Research Foundation (FWO) – strategic basic research doctoral grant 1SC3819N. C. Bartic, G. Callewaert and O. Deschaume acknowledge the financial support by the Flanders Research Foundation (FWO grant G0947.17N) and KU Leuven research grants OT/14/084 and C14/18/061. T. Verbiest acknowledges financial support from the Hercules Foundation, grant AKUL/11/15.
PY - 2021/5/21
Y1 - 2021/5/21
N2 - The optoelectronic properties of semiconductor nanoparticles make them valuable candidates for the long-term monitoring of transmembrane electric fields in excitable cells. In this work, we show that the electric field sensitivity of the fluorescence intensity of type-I and quasi-type-II quantum dots and quantum rods is enhanced under two-photon excitation compared to single-photon excitation. Based on the superior electric field sensitivity of the two-photon excited fluorescence, we demonstrate the ability of quantum dots and rods to track fast switching E-fields. These findings indicate the potential of semiconductor nanoparticles as cellular voltage probes in multiphoton imaging.
AB - The optoelectronic properties of semiconductor nanoparticles make them valuable candidates for the long-term monitoring of transmembrane electric fields in excitable cells. In this work, we show that the electric field sensitivity of the fluorescence intensity of type-I and quasi-type-II quantum dots and quantum rods is enhanced under two-photon excitation compared to single-photon excitation. Based on the superior electric field sensitivity of the two-photon excited fluorescence, we demonstrate the ability of quantum dots and rods to track fast switching E-fields. These findings indicate the potential of semiconductor nanoparticles as cellular voltage probes in multiphoton imaging.
KW - electric field
KW - quantum dot/rod
KW - semiconductor nanoparticle
KW - two-photon fluorescence
KW - voltage sensing
UR - http://www.scopus.com/inward/record.url?scp=85107176495&partnerID=8YFLogxK
U2 - 10.1515/nanoph-2021-0077
DO - 10.1515/nanoph-2021-0077
M3 - Article
VL - 10
SP - 2407
EP - 2420
JO - Nanophotonics
JF - Nanophotonics
SN - 2192-8606
IS - 9
ER -