Details
| Original language | English |
|---|---|
| Pages (from-to) | 3485-3488 |
| Number of pages | 4 |
| Journal | Tetrahedron letters |
| Volume | 50 |
| Issue number | 26 |
| Publication status | Published - 1 Jul 2009 |
Abstract
The synthesis of polyketide segments through the vinylogous Mukaiyama aldol reaction is reported. The use of chiral oxazaborolidines allows using terminal substituted ketene acetals and provides access to extended segments and two new chiral centers.
Keywords
- Enantioselective, Natural products, Oxazaborolidines, Polyketides, Vinylogous Mukaiyama aldol
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Organic Chemistry
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In: Tetrahedron letters, Vol. 50, No. 26, 01.07.2009, p. 3485-3488.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Enantioselective synthesis of polyketide segments through vinylogous Mukaiyama aldol reactions
AU - Simsek, Serkan
AU - Kalesse, Markus
PY - 2009/7/1
Y1 - 2009/7/1
N2 - The synthesis of polyketide segments through the vinylogous Mukaiyama aldol reaction is reported. The use of chiral oxazaborolidines allows using terminal substituted ketene acetals and provides access to extended segments and two new chiral centers.
AB - The synthesis of polyketide segments through the vinylogous Mukaiyama aldol reaction is reported. The use of chiral oxazaborolidines allows using terminal substituted ketene acetals and provides access to extended segments and two new chiral centers.
KW - Enantioselective
KW - Natural products
KW - Oxazaborolidines
KW - Polyketides
KW - Vinylogous Mukaiyama aldol
UR - http://www.scopus.com/inward/record.url?scp=65549123704&partnerID=8YFLogxK
U2 - 10.1016/j.tetlet.2009.03.013
DO - 10.1016/j.tetlet.2009.03.013
M3 - Article
AN - SCOPUS:65549123704
VL - 50
SP - 3485
EP - 3488
JO - Tetrahedron letters
JF - Tetrahedron letters
SN - 0040-4039
IS - 26
ER -