Details
| Original language | English |
|---|---|
| Title of host publication | Diagnostic Optical Spectroscopy in Biomedicine II |
| Pages | 202-213 |
| Number of pages | 12 |
| Publication status | Published - 8 Oct 2003 |
| Event | Diagnostic Optical Spectroscopy in Biomedicine II - Munich, Germany Duration: 24 Jun 2003 → 25 Jun 2003 |
Publication series
| Name | Proceedings of SPIE - The International Society for Optical Engineering |
|---|---|
| Publisher | SPIE |
| Volume | 5141 |
| ISSN (Print) | 0277-786X |
Abstract
A new micro measurement system - according to the principle of the EMPHO-System - has been developed to record tissue remission spectra within the range of 510 to 590 nm. The device hardware basically involves a white LED, optical fibers, and a miniaturized grating spectrometer. In general, exact computation of blood oxygen saturation and relative hemoglobin concentration from these tissue remisson spectra is not possible. The main reason is that - except for oxyhemoglobin and desoxyhemoglobin - many other light-scattering and light-absorbing substances such as dopa-melanin and bilirubin cause measurement errors. A new algorithm for the determination of local blood oxygen saturation and relative hemoglobin concentration from tissue remisson spectra is presented. This method is based on the probability of light photons propagation and reference coefficients. In addition, the algorithm also takes other light-scattering and light-absorbance substances in biological tissue into consideration. The method is compared with the standard procedure of Kubelka and Munk. Among others these two approaches are applied to the tissue remission spectra of ischaemia with subsequent reactive hyperemia. The calculated blood oxygen saturation and relative hemoglobin concentration of both methods are presented and discussed.
Keywords
- Biological tissue, Blood oxygen saturation, Hemoglobin concentration, Kubelka-Munk, Tissue remission spectra
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Physics and Astronomy(all)
- Condensed Matter Physics
- Computer Science(all)
- Computer Science Applications
- Mathematics(all)
- Applied Mathematics
- Engineering(all)
- Electrical and Electronic Engineering
Cite this
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Diagnostic Optical Spectroscopy in Biomedicine II. 2003. p. 202-213 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 5141).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Employing microtechnology for noninvasive determination of local blood oxygen saturation based on tissue remission spectra
AU - Ehret, Gerd
AU - Thiemann, Ignaz
AU - Reithmeier, Eduard
PY - 2003/10/8
Y1 - 2003/10/8
N2 - A new micro measurement system - according to the principle of the EMPHO-System - has been developed to record tissue remission spectra within the range of 510 to 590 nm. The device hardware basically involves a white LED, optical fibers, and a miniaturized grating spectrometer. In general, exact computation of blood oxygen saturation and relative hemoglobin concentration from these tissue remisson spectra is not possible. The main reason is that - except for oxyhemoglobin and desoxyhemoglobin - many other light-scattering and light-absorbing substances such as dopa-melanin and bilirubin cause measurement errors. A new algorithm for the determination of local blood oxygen saturation and relative hemoglobin concentration from tissue remisson spectra is presented. This method is based on the probability of light photons propagation and reference coefficients. In addition, the algorithm also takes other light-scattering and light-absorbance substances in biological tissue into consideration. The method is compared with the standard procedure of Kubelka and Munk. Among others these two approaches are applied to the tissue remission spectra of ischaemia with subsequent reactive hyperemia. The calculated blood oxygen saturation and relative hemoglobin concentration of both methods are presented and discussed.
AB - A new micro measurement system - according to the principle of the EMPHO-System - has been developed to record tissue remission spectra within the range of 510 to 590 nm. The device hardware basically involves a white LED, optical fibers, and a miniaturized grating spectrometer. In general, exact computation of blood oxygen saturation and relative hemoglobin concentration from these tissue remisson spectra is not possible. The main reason is that - except for oxyhemoglobin and desoxyhemoglobin - many other light-scattering and light-absorbing substances such as dopa-melanin and bilirubin cause measurement errors. A new algorithm for the determination of local blood oxygen saturation and relative hemoglobin concentration from tissue remisson spectra is presented. This method is based on the probability of light photons propagation and reference coefficients. In addition, the algorithm also takes other light-scattering and light-absorbance substances in biological tissue into consideration. The method is compared with the standard procedure of Kubelka and Munk. Among others these two approaches are applied to the tissue remission spectra of ischaemia with subsequent reactive hyperemia. The calculated blood oxygen saturation and relative hemoglobin concentration of both methods are presented and discussed.
KW - Biological tissue
KW - Blood oxygen saturation
KW - Hemoglobin concentration
KW - Kubelka-Munk
KW - Tissue remission spectra
UR - http://www.scopus.com/inward/record.url?scp=1342268016&partnerID=8YFLogxK
U2 - 10.1117/12.500052
DO - 10.1117/12.500052
M3 - Conference contribution
AN - SCOPUS:1342268016
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 202
EP - 213
BT - Diagnostic Optical Spectroscopy in Biomedicine II
T2 - Diagnostic Optical Spectroscopy in Biomedicine II
Y2 - 24 June 2003 through 25 June 2003
ER -