Details
| Original language | English |
|---|---|
| Article number | 5545 |
| Journal | Molecules |
| Volume | 25 |
| Issue number | 23 |
| Publication status | Published - 26 Nov 2020 |
Abstract
Phenolic compounds (quercetin, rutin, cyanidin, tangeretin, hesperetin, curcumin, resveratrol, etc.) are known to have health-promoting effects and they are accepted as one of the main proposed nutraceutical group. However, their application is limited owing to the problems related with their stability and water solubility as well as their low bioaccessibility and bioavailability. These limitations can be overcome by encapsulating phenolic compounds by physical, physicochemical and chemical encapsulation techniques. This review focuses on the effects of encapsulation, especially lipid-based techniques (emulsion/nanoemulsion, solid lipid nanoparticles, liposomes/nanoliposomes, etc.), on the digestibility characteristics of phenolic compounds in terms of bioaccessibility and bioavailability.
Keywords
- PMF, bioaccessibility, bioavailability, curcumin, encapsulation, lipid-based delivery systems, polyphenols, resveratrol, Encapsulation, Bioaccessibility, Bioavailability, Lipid-based delivery systems, Resveratrol, Polyphenols, Curcumin
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Analytical Chemistry
- Chemistry(all)
- Chemistry (miscellaneous)
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Medicine
- Chemistry(all)
- Physical and Theoretical Chemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmaceutical Science
- Chemistry(all)
- Organic Chemistry
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In: Molecules, Vol. 25, No. 23, 5545, 26.11.2020.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Effects of lipid-based encapsulation on the bioaccessibility and bioavailability of phenolic compounds
AU - Ozkan, Gulay
AU - Kostka, Tina
AU - Esatbeyoglu, Tuba
AU - Capanoglu, Esra
N1 - Funding information: The publication of this article was funded by the Open Access Fund of the Leibniz Universität Hannover.
PY - 2020/11/26
Y1 - 2020/11/26
N2 - Phenolic compounds (quercetin, rutin, cyanidin, tangeretin, hesperetin, curcumin, resveratrol, etc.) are known to have health-promoting effects and they are accepted as one of the main proposed nutraceutical group. However, their application is limited owing to the problems related with their stability and water solubility as well as their low bioaccessibility and bioavailability. These limitations can be overcome by encapsulating phenolic compounds by physical, physicochemical and chemical encapsulation techniques. This review focuses on the effects of encapsulation, especially lipid-based techniques (emulsion/nanoemulsion, solid lipid nanoparticles, liposomes/nanoliposomes, etc.), on the digestibility characteristics of phenolic compounds in terms of bioaccessibility and bioavailability.
AB - Phenolic compounds (quercetin, rutin, cyanidin, tangeretin, hesperetin, curcumin, resveratrol, etc.) are known to have health-promoting effects and they are accepted as one of the main proposed nutraceutical group. However, their application is limited owing to the problems related with their stability and water solubility as well as their low bioaccessibility and bioavailability. These limitations can be overcome by encapsulating phenolic compounds by physical, physicochemical and chemical encapsulation techniques. This review focuses on the effects of encapsulation, especially lipid-based techniques (emulsion/nanoemulsion, solid lipid nanoparticles, liposomes/nanoliposomes, etc.), on the digestibility characteristics of phenolic compounds in terms of bioaccessibility and bioavailability.
KW - PMF
KW - bioaccessibility
KW - bioavailability
KW - curcumin
KW - encapsulation
KW - lipid-based delivery systems
KW - polyphenols
KW - resveratrol
KW - Encapsulation
KW - Bioaccessibility
KW - Bioavailability
KW - Lipid-based delivery systems
KW - Resveratrol
KW - Polyphenols
KW - Curcumin
UR - http://www.scopus.com/inward/record.url?scp=85097036869&partnerID=8YFLogxK
U2 - 10.3390/molecules25235545
DO - 10.3390/molecules25235545
M3 - Article
C2 - 33256012
VL - 25
JO - Molecules
JF - Molecules
SN - 1420-3049
IS - 23
M1 - 5545
ER -