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Easy Semantification of Bioassays

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Authors

  • Marco Anteghini
  • Jennifer D’Souza
  • Vitor A.P.Martins dos Santos
  • Sören Auer

External Research Organisations

  • LifeGlimmer GmbH
  • Wageningen University and Research
  • German National Library of Science and Technology (TIB)
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  • Citations
    • Citation Indexes: 1
  • Captures
    • Readers: 3
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Details

Original languageEnglish
Title of host publicationAIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers
EditorsStefania Bandini, Francesca Gasparini, Viviana Mascardi, Matteo Palmonari, Giuseppe Vizzari
PublisherSpringer Science and Business Media Deutschland GmbH
Pages198-212
Number of pages15
ISBN (electronic)978-3-031-08421-8
ISBN (print)9783031084201
Publication statusPublished - 2022
Externally publishedYes
Event20th International Conference of the Italian Association for Artificial Intelligence, AIxIA 2021 - Virtual, Online
Duration: 1 Dec 20213 Dec 2021

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume13196 LNAI
ISSN (Print)0302-9743
ISSN (electronic)1611-3349

Abstract

Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. We propose a solution for automatically semantifying biological assays. Our solution contrasts the problem of automated semantification as labeling versus clustering where the two methods are on opposite ends of the method complexity spectrum. Characteristically modeling our problem, we find the clustering solution significantly outperforms a deep neural network state-of-the-art labeling approach. This novel contribution is based on two factors: 1) a learning objective closely modeled after the data outperforms an alternative approach with sophisticated semantic modeling; 2) automatically semantifying biological assays achieves a high performance F1 of nearly 83%, which to our knowledge is the first reported standardized evaluation of the task offering a strong benchmark model.

Keywords

    Automatic semantification, Bioassays, Clustering, Labeling, Open Research Knowledge Graph, Open science graphs, Supervised learning, Unsupervised learning

ASJC Scopus subject areas

Cite this

Easy Semantification of Bioassays. / Anteghini, Marco; D’Souza, Jennifer; dos Santos, Vitor A.P.Martins et al.
AIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers. ed. / Stefania Bandini; Francesca Gasparini; Viviana Mascardi; Matteo Palmonari; Giuseppe Vizzari. Springer Science and Business Media Deutschland GmbH, 2022. p. 198-212 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 13196 LNAI).

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Anteghini, M, D’Souza, J, dos Santos, VAPM & Auer, S 2022, Easy Semantification of Bioassays. in S Bandini, F Gasparini, V Mascardi, M Palmonari & G Vizzari (eds), AIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 13196 LNAI, Springer Science and Business Media Deutschland GmbH, pp. 198-212, 20th International Conference of the Italian Association for Artificial Intelligence, AIxIA 2021, Virtual, Online, 1 Dec 2021. https://doi.org/10.1007/978-3-031-08421-8_14, https://doi.org/10.48550/arXiv.2111.15182
Anteghini, M., D’Souza, J., dos Santos, V. A. P. M., & Auer, S. (2022). Easy Semantification of Bioassays. In S. Bandini, F. Gasparini, V. Mascardi, M. Palmonari, & G. Vizzari (Eds.), AIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers (pp. 198-212). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 13196 LNAI). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-031-08421-8_14, https://doi.org/10.48550/arXiv.2111.15182
Anteghini M, D’Souza J, dos Santos VAPM, Auer S. Easy Semantification of Bioassays. In Bandini S, Gasparini F, Mascardi V, Palmonari M, Vizzari G, editors, AIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers. Springer Science and Business Media Deutschland GmbH. 2022. p. 198-212. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). Epub 2022 Jul 19. doi: 10.1007/978-3-031-08421-8_14, 10.48550/arXiv.2111.15182
Anteghini, Marco ; D’Souza, Jennifer ; dos Santos, Vitor A.P.Martins et al. / Easy Semantification of Bioassays. AIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers. editor / Stefania Bandini ; Francesca Gasparini ; Viviana Mascardi ; Matteo Palmonari ; Giuseppe Vizzari. Springer Science and Business Media Deutschland GmbH, 2022. pp. 198-212 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).
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title = "Easy Semantification of Bioassays",
abstract = "Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. We propose a solution for automatically semantifying biological assays. Our solution contrasts the problem of automated semantification as labeling versus clustering where the two methods are on opposite ends of the method complexity spectrum. Characteristically modeling our problem, we find the clustering solution significantly outperforms a deep neural network state-of-the-art labeling approach. This novel contribution is based on two factors: 1) a learning objective closely modeled after the data outperforms an alternative approach with sophisticated semantic modeling; 2) automatically semantifying biological assays achieves a high performance F1 of nearly 83%, which to our knowledge is the first reported standardized evaluation of the task offering a strong benchmark model.",
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Download

TY - GEN

T1 - Easy Semantification of Bioassays

AU - Anteghini, Marco

AU - D’Souza, Jennifer

AU - dos Santos, Vitor A.P.Martins

AU - Auer, Sören

N1 - Funding Information: Supported by TIB Leibniz Information Centre for Science and Technology, the EU H2020 ERC project ScienceGRaph (GA ID: 819536) and the ITN PERICO (GA ID: 812968).

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Y1 - 2022

N2 - Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. We propose a solution for automatically semantifying biological assays. Our solution contrasts the problem of automated semantification as labeling versus clustering where the two methods are on opposite ends of the method complexity spectrum. Characteristically modeling our problem, we find the clustering solution significantly outperforms a deep neural network state-of-the-art labeling approach. This novel contribution is based on two factors: 1) a learning objective closely modeled after the data outperforms an alternative approach with sophisticated semantic modeling; 2) automatically semantifying biological assays achieves a high performance F1 of nearly 83%, which to our knowledge is the first reported standardized evaluation of the task offering a strong benchmark model.

AB - Biological data and knowledge bases increasingly rely on Semantic Web technologies and the use of knowledge graphs for data integration, retrieval and federated queries. We propose a solution for automatically semantifying biological assays. Our solution contrasts the problem of automated semantification as labeling versus clustering where the two methods are on opposite ends of the method complexity spectrum. Characteristically modeling our problem, we find the clustering solution significantly outperforms a deep neural network state-of-the-art labeling approach. This novel contribution is based on two factors: 1) a learning objective closely modeled after the data outperforms an alternative approach with sophisticated semantic modeling; 2) automatically semantifying biological assays achieves a high performance F1 of nearly 83%, which to our knowledge is the first reported standardized evaluation of the task offering a strong benchmark model.

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KW - Bioassays

KW - Clustering

KW - Labeling

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DO - 10.1007/978-3-031-08421-8_14

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T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

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BT - AIxIA 2021 – Advances in Artificial Intelligence - 20th International Conference of the Italian Association for Artificial Intelligence, Revised Selected Papers

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