Details
| Original language | English |
|---|---|
| Pages (from-to) | 929-930 |
| Number of pages | 2 |
| Journal | Cell Chemical Biology |
| Volume | 25 |
| Issue number | 8 |
| Publication status | Published - 16 Aug 2018 |
Abstract
In this issue of Cell Chemical Biology, Wong et al. (2018) identify several dysregulators of a key mitochondrial protease: casein lytic protease P (ClpP). These dysregulators were found to trigger programmed cell death and may offer fresh avenues for the development of novel cancer therapeutics.
Keywords
- Anti-Bacterial Agents, Caseins, Cell Death, Endopeptidase Clp, Humans, Mitochondria
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Medicine
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
- Biochemistry, Genetics and Molecular Biology(all)
- Clinical Biochemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmacology
Sustainable Development Goals
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In: Cell Chemical Biology, Vol. 25, No. 8, 16.08.2018, p. 929-930.
Research output: Contribution to journal › Survey paper › Research › peer review
}
TY - JOUR
T1 - Dysregulating ClpP
T2 - From Antibiotics to Anticancer?
AU - Dougan, David A.
AU - Hantke, Ingo
AU - Turgay, Kürşad
N1 - Funding Information: I.H. and K.T. are supported by the Hannover School for Biomolecular Drug Research and the Deutsche Forschungsgemeinschaft . The authors declare no competing interests. Publisher Copyright: © Elsevier Ltd Copyright: Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2018/8/16
Y1 - 2018/8/16
N2 - In this issue of Cell Chemical Biology, Wong et al. (2018) identify several dysregulators of a key mitochondrial protease: casein lytic protease P (ClpP). These dysregulators were found to trigger programmed cell death and may offer fresh avenues for the development of novel cancer therapeutics.
AB - In this issue of Cell Chemical Biology, Wong et al. (2018) identify several dysregulators of a key mitochondrial protease: casein lytic protease P (ClpP). These dysregulators were found to trigger programmed cell death and may offer fresh avenues for the development of novel cancer therapeutics.
KW - Anti-Bacterial Agents
KW - Caseins
KW - Cell Death
KW - Endopeptidase Clp
KW - Humans
KW - Mitochondria
UR - http://www.scopus.com/inward/record.url?scp=85051064847&partnerID=8YFLogxK
U2 - 10.1016/j.chembiol.2018.08.002
DO - 10.1016/j.chembiol.2018.08.002
M3 - Survey paper
C2 - 30118671
AN - SCOPUS:85051064847
VL - 25
SP - 929
EP - 930
JO - Cell Chemical Biology
JF - Cell Chemical Biology
SN - 2451-9456
IS - 8
ER -