Dynamics of growth in batch and continuous cultures of Saccharomyces cerevisiae during shifts from aerobiosis to anaerobiosis and reverse

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Authors

  • G. Auling
  • K. H. Bellgardt
  • H. Diekmann
  • M. Thoma

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Original languageEnglish
Pages (from-to)353-357
Number of pages5
JournalApplied Microbiology and Biotechnology
Volume19
Issue number5
Publication statusPublished - May 1984

Abstract

Saccharomycescerevisiae H 1022 was cultivated in batch and continuous culture on a glucose substrate. The yeast was subjected to a sudden change from aerobic to anaerobic growth conditions by switching the inlet-gas stream from air to dinitrogen. The dynamics of growth and product formation during the periods of adaptation were studied. A structured growth model based on Monod-Blackman-kinetics was applied to simulate these shift-experiments. The immediate switch of the yeast to maximum anaerobic growth and ethanol production predicted by this model was confirmed very well in the chemostat-experiments. However, a slow adaptation was evident for the switch from anaerobiosis back to aerobiosis.

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Dynamics of growth in batch and continuous cultures of Saccharomyces cerevisiae during shifts from aerobiosis to anaerobiosis and reverse. / Auling, G.; Bellgardt, K. H.; Diekmann, H. et al.
In: Applied Microbiology and Biotechnology, Vol. 19, No. 5, 05.1984, p. 353-357.

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