Details
| Original language | English |
|---|---|
| Title of host publication | Successful Drug Discovery |
| Publisher | Wiley-Blackwell |
| Pages | 3-46 |
| Number of pages | 44 |
| Volume | 5 |
| ISBN (electronic) | 9783527826872 |
| ISBN (print) | 9783527347544 |
| Publication status | Published - 22 Mar 2021 |
Abstract
Despite the tremendous financial effort, the success rates of industrial drug discovery efforts continue to be unsustainably low. Academic drug discovery on the other hand provides many success stories of discovery of new medications to treat human diseases and the opening of new therapeutic paradigms to tackle previously incurable conditions. This chapter will illustrate this contribution by highlighting examples for the successful discovery of new medicines and discussing success criteria and specifics of the respective approach. Furthermore, limitations and opportunities will be discussed. Academic drug discovery can and will represent an important factor for improving current therapies, establish novel treatment concepts, and touch new territory for improving on treatment for difficult to impossible to treat human diseases, thus helping to improve the condition and extend the lifespan of many patients.
Keywords
- Academia, Academic drug discovery, breakthrough therapies, case stories, Drug discovery, novel approaches, success stories
ASJC Scopus subject areas
Sustainable Development Goals
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Successful Drug Discovery. Vol. 5 Wiley-Blackwell, 2021. p. 3-46.
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
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TY - CHAP
T1 - Drug Discovery in Academia
AU - Plettenburg, Oliver
PY - 2021/3/22
Y1 - 2021/3/22
N2 - Despite the tremendous financial effort, the success rates of industrial drug discovery efforts continue to be unsustainably low. Academic drug discovery on the other hand provides many success stories of discovery of new medications to treat human diseases and the opening of new therapeutic paradigms to tackle previously incurable conditions. This chapter will illustrate this contribution by highlighting examples for the successful discovery of new medicines and discussing success criteria and specifics of the respective approach. Furthermore, limitations and opportunities will be discussed. Academic drug discovery can and will represent an important factor for improving current therapies, establish novel treatment concepts, and touch new territory for improving on treatment for difficult to impossible to treat human diseases, thus helping to improve the condition and extend the lifespan of many patients.
AB - Despite the tremendous financial effort, the success rates of industrial drug discovery efforts continue to be unsustainably low. Academic drug discovery on the other hand provides many success stories of discovery of new medications to treat human diseases and the opening of new therapeutic paradigms to tackle previously incurable conditions. This chapter will illustrate this contribution by highlighting examples for the successful discovery of new medicines and discussing success criteria and specifics of the respective approach. Furthermore, limitations and opportunities will be discussed. Academic drug discovery can and will represent an important factor for improving current therapies, establish novel treatment concepts, and touch new territory for improving on treatment for difficult to impossible to treat human diseases, thus helping to improve the condition and extend the lifespan of many patients.
KW - Academia
KW - Academic drug discovery
KW - breakthrough therapies
KW - case stories
KW - Drug discovery
KW - novel approaches
KW - success stories
UR - http://www.scopus.com/inward/record.url?scp=85153663144&partnerID=8YFLogxK
U2 - 10.1002/9783527826872.ch1
DO - 10.1002/9783527826872.ch1
M3 - Contribution to book/anthology
AN - SCOPUS:85153663144
SN - 9783527347544
VL - 5
SP - 3
EP - 46
BT - Successful Drug Discovery
PB - Wiley-Blackwell
ER -