Details
| Original language | English |
|---|---|
| Article number | 5719 |
| Pages (from-to) | 5719 |
| Journal | Scientific reports |
| Volume | 14 |
| Issue number | 1 |
| Publication status | Published - 8 Mar 2024 |
Abstract
Prosthetic implants, particularly hip endoprostheses, often lead to stress shielding because of a mismatch in compliance between the bone and the implant material, adversely affecting the implant's longevity and effectiveness. Therefore, this work aimed to demonstrate a computationally efficient method for density-based topology optimization of homogenized lattice structures in a patient-specific hip endoprosthesis. Thus, the root mean square error (RMSE) of the stress deviations between the physiological femur model and the optimized total hip arthroplasty (THA) model compared to an unoptimized-THA model could be reduced by 81 % and 66 % in Gruen zone (GZ) 6 and 7. However, the method relies on homogenized finite element (FE) models that only use a simplified representation of the microstructural geometry of the bone and implant. The topology-optimized hip endoprosthesis with graded lattice structures was synthesized using algorithmic design and analyzed in a virtual implanted state using micro-finite element (micro-FE) analysis to validate the optimization method. Homogenized FE and micro-FE models were compared based on averaged von Mises stresses in multiple regions of interest. A strong correlation (CCC > 0.97) was observed, indicating that optimizing homogenized lattice structures yields reliable outcomes. The graded implant was additively manufactured to ensure the topology-optimized result's feasibility.
Keywords
- Humans, Hip Prosthesis, Prosthesis Design, Arthroplasty, Replacement, Hip/methods, Femur, Finite Element Analysis, Stress, Mechanical, Lattice structures, Topology optimization, Micro-FE, Additive manufacturing, Individualized hip endoprosthesis
ASJC Scopus subject areas
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In: Scientific reports, Vol. 14, No. 1, 5719, 08.03.2024, p. 5719.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Development of a density-based topology optimization of homogenized lattice structures for individualized hip endoprostheses and validation using micro-FE
AU - Müller, Patrik
AU - Synek, Alexander
AU - Stauß, Timo
AU - Steinnagel, Carl
AU - Ehlers, Tobias
AU - Gembarski, Paul Christoph
AU - Pahr, Dieter
AU - Lachmayer, Roland
N1 - Publisher Copyright: © The Author(s) 2024.
PY - 2024/3/8
Y1 - 2024/3/8
N2 - Prosthetic implants, particularly hip endoprostheses, often lead to stress shielding because of a mismatch in compliance between the bone and the implant material, adversely affecting the implant's longevity and effectiveness. Therefore, this work aimed to demonstrate a computationally efficient method for density-based topology optimization of homogenized lattice structures in a patient-specific hip endoprosthesis. Thus, the root mean square error (RMSE) of the stress deviations between the physiological femur model and the optimized total hip arthroplasty (THA) model compared to an unoptimized-THA model could be reduced by 81 % and 66 % in Gruen zone (GZ) 6 and 7. However, the method relies on homogenized finite element (FE) models that only use a simplified representation of the microstructural geometry of the bone and implant. The topology-optimized hip endoprosthesis with graded lattice structures was synthesized using algorithmic design and analyzed in a virtual implanted state using micro-finite element (micro-FE) analysis to validate the optimization method. Homogenized FE and micro-FE models were compared based on averaged von Mises stresses in multiple regions of interest. A strong correlation (CCC > 0.97) was observed, indicating that optimizing homogenized lattice structures yields reliable outcomes. The graded implant was additively manufactured to ensure the topology-optimized result's feasibility.
AB - Prosthetic implants, particularly hip endoprostheses, often lead to stress shielding because of a mismatch in compliance between the bone and the implant material, adversely affecting the implant's longevity and effectiveness. Therefore, this work aimed to demonstrate a computationally efficient method for density-based topology optimization of homogenized lattice structures in a patient-specific hip endoprosthesis. Thus, the root mean square error (RMSE) of the stress deviations between the physiological femur model and the optimized total hip arthroplasty (THA) model compared to an unoptimized-THA model could be reduced by 81 % and 66 % in Gruen zone (GZ) 6 and 7. However, the method relies on homogenized finite element (FE) models that only use a simplified representation of the microstructural geometry of the bone and implant. The topology-optimized hip endoprosthesis with graded lattice structures was synthesized using algorithmic design and analyzed in a virtual implanted state using micro-finite element (micro-FE) analysis to validate the optimization method. Homogenized FE and micro-FE models were compared based on averaged von Mises stresses in multiple regions of interest. A strong correlation (CCC > 0.97) was observed, indicating that optimizing homogenized lattice structures yields reliable outcomes. The graded implant was additively manufactured to ensure the topology-optimized result's feasibility.
KW - Humans
KW - Hip Prosthesis
KW - Prosthesis Design
KW - Arthroplasty, Replacement, Hip/methods
KW - Femur
KW - Finite Element Analysis
KW - Stress, Mechanical
KW - Lattice structures
KW - Topology optimization
KW - Micro-FE
KW - Additive manufacturing
KW - Individualized hip endoprosthesis
UR - http://www.scopus.com/inward/record.url?scp=85187185453&partnerID=8YFLogxK
U2 - 10.1038/s41598-024-56327-4
DO - 10.1038/s41598-024-56327-4
M3 - Article
C2 - 38459092
VL - 14
SP - 5719
JO - Scientific reports
JF - Scientific reports
SN - 2045-2322
IS - 1
M1 - 5719
ER -