Details
| Original language | English |
|---|---|
| Pages (from-to) | 17-21 |
| Number of pages | 5 |
| Journal | Biosensors and Bioelectronics |
| Volume | 9 |
| Issue number | 1 |
| Publication status | Published - 1994 |
Abstract
New biosensors were developed by immobilizing enzymes on simple EIS (Electrolyte Insulator Semiconductor) layer structures. These EIS-structures produced by means of semiconductor technologies are either pH-(Si/SiO2/Si3N4/Ta2O5 layers) or pF-sensitive (Si/SiO2/Si3N4/LaF3 layers). A schematic of the layered structure is shown in Fig. 1. The basic principle for measurements with the modified EIS-layer structures is the change in capacitance in dependence on the concentration of H+ or F- ions. Measurements were made by using a C/V-measuring instrument in a "constant charge mode". These biosensors as well as a reference electrode were integrated into an FIA-system (Flow Injection Analyser) and the concentrations of penicillin and urea (with pH-sensor) and H2O2 and glucose (with pF-sensor) were determined.
Keywords
- C/V measurements, EIS-structures, enzyme sensor, FIA-system
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Biochemistry, Genetics and Molecular Biology(all)
- Biophysics
- Engineering(all)
- Biomedical Engineering
- Chemistry(all)
- Electrochemistry
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In: Biosensors and Bioelectronics, Vol. 9, No. 1, 1994, p. 17-21.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Development and application of a new enzyme sensor type based on the EIS-capacitance structure for bioprocess control
AU - Beyer, M.
AU - Menzel, C.
AU - Quack, R.
AU - Scheper, T.
AU - Schügerl, K.
AU - Treichel, W.
AU - Voigt, H.
AU - Ullrich, M.
AU - Ferretti, R.
PY - 1994
Y1 - 1994
N2 - New biosensors were developed by immobilizing enzymes on simple EIS (Electrolyte Insulator Semiconductor) layer structures. These EIS-structures produced by means of semiconductor technologies are either pH-(Si/SiO2/Si3N4/Ta2O5 layers) or pF-sensitive (Si/SiO2/Si3N4/LaF3 layers). A schematic of the layered structure is shown in Fig. 1. The basic principle for measurements with the modified EIS-layer structures is the change in capacitance in dependence on the concentration of H+ or F- ions. Measurements were made by using a C/V-measuring instrument in a "constant charge mode". These biosensors as well as a reference electrode were integrated into an FIA-system (Flow Injection Analyser) and the concentrations of penicillin and urea (with pH-sensor) and H2O2 and glucose (with pF-sensor) were determined.
AB - New biosensors were developed by immobilizing enzymes on simple EIS (Electrolyte Insulator Semiconductor) layer structures. These EIS-structures produced by means of semiconductor technologies are either pH-(Si/SiO2/Si3N4/Ta2O5 layers) or pF-sensitive (Si/SiO2/Si3N4/LaF3 layers). A schematic of the layered structure is shown in Fig. 1. The basic principle for measurements with the modified EIS-layer structures is the change in capacitance in dependence on the concentration of H+ or F- ions. Measurements were made by using a C/V-measuring instrument in a "constant charge mode". These biosensors as well as a reference electrode were integrated into an FIA-system (Flow Injection Analyser) and the concentrations of penicillin and urea (with pH-sensor) and H2O2 and glucose (with pF-sensor) were determined.
KW - C/V measurements
KW - EIS-structures
KW - enzyme sensor
KW - FIA-system
UR - http://www.scopus.com/inward/record.url?scp=0028266596&partnerID=8YFLogxK
U2 - 10.1016/0956-5663(94)80010-3
DO - 10.1016/0956-5663(94)80010-3
M3 - Article
AN - SCOPUS:0028266596
VL - 9
SP - 17
EP - 21
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
SN - 0956-5663
IS - 1
ER -