Details
| Original language | English |
|---|---|
| Title of host publication | International Youth Conference on Electronics, Telecommunications and Information Technologies |
| Subtitle of host publication | Proceedings of the YETI 2021 |
| Editors | Elena Velichko, Viktoria Kapralova, Platon Karaseov, Sergey Zavjalov, Pablo Angueira, Sergey Andreev |
| Publisher | Springer Science and Business Media Deutschland GmbH |
| Pages | 301-315 |
| Number of pages | 15 |
| ISBN (print) | 9783030811181 |
| Publication status | Published - 2022 |
| Event | International Youth Conference on Electronics, Telecommunications, and Information Technologies, YETI 2021 - Saint Petersburg, Russian Federation Duration: 22 Apr 2021 → 23 Apr 2021 |
Publication series
| Name | Springer Proceedings in Physics |
|---|---|
| Volume | 268 |
| ISSN (Print) | 0930-8989 |
| ISSN (electronic) | 1867-4941 |
Abstract
Laser induced thermal therapy (LITT) emerged in recent years as a minimal invasive treatment method for otherwise oftentimes inoperable brain tumors, such as glioblastomas. During the thermal ablation process, the procedure carries the risk of destroying healthy brain tissue adjacent to the tumor. Limitations in the spatial distribution of the real-time monitoring MR thermography system currently allow only a rough representation of the damage zone during surgery. For this reason, improved pre-operative simulations of tissue heating and the resulting tissue damage could be valuable to optimize clinical treatment protocols while minimizing the risks of the procedure. In this study a method is presented, to simulate the ablation process of the LITT with the finite elements method (FEM) using the simulation software COMSOL MULTIPHYSICS. Thereby the temperature distribution is displayed and, based on this, the extent of the tissue damage during the process is simulated. Therefore, relevant parameters for the ablation process, such as optical and thermal properties, blood per-fusion, and the interface between healthy and tumor tissue were investigated and their influence on temperature distribution and extent of tissue damage was described.
Keywords
- Finite elements method, Laser in medicine, LITT, Minimal invasive surgery
ASJC Scopus subject areas
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International Youth Conference on Electronics, Telecommunications and Information Technologies: Proceedings of the YETI 2021. ed. / Elena Velichko; Viktoria Kapralova; Platon Karaseov; Sergey Zavjalov; Pablo Angueira; Sergey Andreev. Springer Science and Business Media Deutschland GmbH, 2022. p. 301-315 (Springer Proceedings in Physics; Vol. 268).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Destruction of Unresectable Brain Tumors
T2 - International Youth Conference on Electronics, Telecommunications, and Information Technologies, YETI 2021
AU - Hentschel, Gesine
AU - Johansson, Johannes
AU - Winkler, Christina
AU - Glasmacher, Birgit
AU - Wårdell, Karin
N1 - Funding Information: The authors want to thank the Dr. J?rgen und Irmgard Ulderup Foundation and the ERASMUS+ program for the financial support of this study.
PY - 2022
Y1 - 2022
N2 - Laser induced thermal therapy (LITT) emerged in recent years as a minimal invasive treatment method for otherwise oftentimes inoperable brain tumors, such as glioblastomas. During the thermal ablation process, the procedure carries the risk of destroying healthy brain tissue adjacent to the tumor. Limitations in the spatial distribution of the real-time monitoring MR thermography system currently allow only a rough representation of the damage zone during surgery. For this reason, improved pre-operative simulations of tissue heating and the resulting tissue damage could be valuable to optimize clinical treatment protocols while minimizing the risks of the procedure. In this study a method is presented, to simulate the ablation process of the LITT with the finite elements method (FEM) using the simulation software COMSOL MULTIPHYSICS. Thereby the temperature distribution is displayed and, based on this, the extent of the tissue damage during the process is simulated. Therefore, relevant parameters for the ablation process, such as optical and thermal properties, blood per-fusion, and the interface between healthy and tumor tissue were investigated and their influence on temperature distribution and extent of tissue damage was described.
AB - Laser induced thermal therapy (LITT) emerged in recent years as a minimal invasive treatment method for otherwise oftentimes inoperable brain tumors, such as glioblastomas. During the thermal ablation process, the procedure carries the risk of destroying healthy brain tissue adjacent to the tumor. Limitations in the spatial distribution of the real-time monitoring MR thermography system currently allow only a rough representation of the damage zone during surgery. For this reason, improved pre-operative simulations of tissue heating and the resulting tissue damage could be valuable to optimize clinical treatment protocols while minimizing the risks of the procedure. In this study a method is presented, to simulate the ablation process of the LITT with the finite elements method (FEM) using the simulation software COMSOL MULTIPHYSICS. Thereby the temperature distribution is displayed and, based on this, the extent of the tissue damage during the process is simulated. Therefore, relevant parameters for the ablation process, such as optical and thermal properties, blood per-fusion, and the interface between healthy and tumor tissue were investigated and their influence on temperature distribution and extent of tissue damage was described.
KW - Finite elements method
KW - Laser in medicine
KW - LITT
KW - Minimal invasive surgery
UR - http://www.scopus.com/inward/record.url?scp=85124272787&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-81119-8_31
DO - 10.1007/978-3-030-81119-8_31
M3 - Conference contribution
AN - SCOPUS:85124272787
SN - 9783030811181
T3 - Springer Proceedings in Physics
SP - 301
EP - 315
BT - International Youth Conference on Electronics, Telecommunications and Information Technologies
A2 - Velichko, Elena
A2 - Kapralova, Viktoria
A2 - Karaseov, Platon
A2 - Zavjalov, Sergey
A2 - Angueira, Pablo
A2 - Andreev, Sergey
PB - Springer Science and Business Media Deutschland GmbH
Y2 - 22 April 2021 through 23 April 2021
ER -