Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling

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Authors

  • Johann Moschner
  • Anna Chentsova
  • Nicole Eilert
  • Irene Rovardi
  • Philipp Heretsch
  • Athanassios Giannis

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Original languageEnglish
Pages (from-to)2328-2335
JournalBeilstein Journal of Organic Chemistry
Volume9
Publication statusPublished - 31 Oct 2013

Keywords

    cyclopamine, hedgehog signaling pathway, natural products, steroidal alkaloids, structure-activity relationship

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Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling. / Moschner, Johann; Chentsova, Anna; Eilert, Nicole et al.
In: Beilstein Journal of Organic Chemistry, Vol. 9, 31.10.2013, p. 2328-2335.

Research output: Contribution to journalArticleResearchpeer review

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title = "Cyclopamine analogs bearing exocyclic methylenes are highly potent and acid-stable inhibitors of hedgehog signaling",
keywords = "cyclopamine, hedgehog signaling pathway, natural products, steroidal alkaloids, structure-activity relationship",
author = "Johann Moschner and Anna Chentsova and Nicole Eilert and Irene Rovardi and Philipp Heretsch and Athanassios Giannis",
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AU - Moschner, Johann

AU - Chentsova, Anna

AU - Eilert, Nicole

AU - Rovardi, Irene

AU - Heretsch, Philipp

AU - Giannis, Athanassios

PY - 2013/10/31

Y1 - 2013/10/31

KW - cyclopamine

KW - hedgehog signaling pathway

KW - natural products

KW - steroidal alkaloids

KW - structure-activity relationship

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DO - 10.3762/bjoc.9.267

M3 - Article

VL - 9

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JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

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