Details
| Original language | English |
|---|---|
| Pages (from-to) | 446-466 |
| Number of pages | 21 |
| Journal | Journal of Occupational and Environmental Hygiene |
| Volume | 16 |
| Issue number | 7 |
| Early online date | 17 May 2019 |
| Publication status | Published - 3 Jul 2019 |
Abstract
Although isocyanates are increasingly used in manufacturing and workplace exposure to isocyanates is widely recognized as one of the most frequent causes for occupational lung and skin diseases, little is known about the economic burden on the affected individual and the society. This study provides an overview on costs of occupational diseases related to isocyanates. We performed a systematic literature search of studies in the electronic databases of the German Institute of Medical Documentation and Information, and the Canadian Centre for Occupational Health and Safety. We extracted the key characteristics of the studies and performed a study quality assessment. We identified eight studies on the costs of illness, of which five focused on occupational lung diseases and three on occupational skin diseases. Further, eight studies calculated loss of income/compensation payments. Out of the 16 identified articles, only two reported costs directly attributable to isocyanate-induced diseases (asthma). Studies were hardly comparable because they differed substantially in their methodological approaches. Moreover, the quality assessment of the studies revealed substantial limitations. While a wide range of isocyanate-related costs was identified, consequences of isocyanate-related occupational diseases were considerable in terms of societal costs and loss of income. In most studies, indirect costs were the main cost driver. There is a need for high-quality cost of illness studies on isocyanate-induced diseases stratified by degree of severity and sex. Such studies provide valuable information to develop preventive strategies and set priorities for measures to lower the burden of professional health risks.
Keywords
- Costs of illness, economic consequences, isocyanates, loss of income, occupational attributable health costs, occupational respiratory disease, occupational skin diseases
ASJC Scopus subject areas
- Medicine(all)
- Public Health, Environmental and Occupational Health
Sustainable Development Goals
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In: Journal of Occupational and Environmental Hygiene, Vol. 16, No. 7, 03.07.2019, p. 446-466.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Costs of isocyanate-related occupational diseases
T2 - A systematic review
AU - Kreis, Kristine
AU - Aumann-Suslin, Ines
AU - Lüdeke, Andreas
AU - Wegewitz, Uta
AU - Zeidler, Jan
AU - Graf von der Schulenburg, Johann-Matthias
N1 - Funding Information: This study was financed by the German Federal Institute for Occupational Safety and Health (BAuA).
PY - 2019/7/3
Y1 - 2019/7/3
N2 - Although isocyanates are increasingly used in manufacturing and workplace exposure to isocyanates is widely recognized as one of the most frequent causes for occupational lung and skin diseases, little is known about the economic burden on the affected individual and the society. This study provides an overview on costs of occupational diseases related to isocyanates. We performed a systematic literature search of studies in the electronic databases of the German Institute of Medical Documentation and Information, and the Canadian Centre for Occupational Health and Safety. We extracted the key characteristics of the studies and performed a study quality assessment. We identified eight studies on the costs of illness, of which five focused on occupational lung diseases and three on occupational skin diseases. Further, eight studies calculated loss of income/compensation payments. Out of the 16 identified articles, only two reported costs directly attributable to isocyanate-induced diseases (asthma). Studies were hardly comparable because they differed substantially in their methodological approaches. Moreover, the quality assessment of the studies revealed substantial limitations. While a wide range of isocyanate-related costs was identified, consequences of isocyanate-related occupational diseases were considerable in terms of societal costs and loss of income. In most studies, indirect costs were the main cost driver. There is a need for high-quality cost of illness studies on isocyanate-induced diseases stratified by degree of severity and sex. Such studies provide valuable information to develop preventive strategies and set priorities for measures to lower the burden of professional health risks.
AB - Although isocyanates are increasingly used in manufacturing and workplace exposure to isocyanates is widely recognized as one of the most frequent causes for occupational lung and skin diseases, little is known about the economic burden on the affected individual and the society. This study provides an overview on costs of occupational diseases related to isocyanates. We performed a systematic literature search of studies in the electronic databases of the German Institute of Medical Documentation and Information, and the Canadian Centre for Occupational Health and Safety. We extracted the key characteristics of the studies and performed a study quality assessment. We identified eight studies on the costs of illness, of which five focused on occupational lung diseases and three on occupational skin diseases. Further, eight studies calculated loss of income/compensation payments. Out of the 16 identified articles, only two reported costs directly attributable to isocyanate-induced diseases (asthma). Studies were hardly comparable because they differed substantially in their methodological approaches. Moreover, the quality assessment of the studies revealed substantial limitations. While a wide range of isocyanate-related costs was identified, consequences of isocyanate-related occupational diseases were considerable in terms of societal costs and loss of income. In most studies, indirect costs were the main cost driver. There is a need for high-quality cost of illness studies on isocyanate-induced diseases stratified by degree of severity and sex. Such studies provide valuable information to develop preventive strategies and set priorities for measures to lower the burden of professional health risks.
KW - Costs of illness
KW - economic consequences
KW - isocyanates
KW - loss of income
KW - occupational attributable health costs
KW - occupational respiratory disease
KW - occupational skin diseases
UR - http://www.scopus.com/inward/record.url?scp=85067598680&partnerID=8YFLogxK
U2 - 10.1080/15459624.2019.1609005
DO - 10.1080/15459624.2019.1609005
M3 - Article
C2 - 31100044
AN - SCOPUS:85067598680
VL - 16
SP - 446
EP - 466
JO - Journal of Occupational and Environmental Hygiene
JF - Journal of Occupational and Environmental Hygiene
SN - 1545-9624
IS - 7
ER -