Confocal raman microscopy in VIS for analysing conformational changes in channel proteins

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Original languageEnglish
Title of host publication2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019
ISBN (electronic)9781728104690
Publication statusPublished - 2019
Event2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019 - Munich, Germany
Duration: 23 Jun 201927 Jun 2019

Abstract

Ion channels are crucial proteins of all cells capable of generating electrical signals, responsible for converting chemical or mechanical messages into electrical signals by rapidly altering the ion concentration within the cell upon activation of the channel gate. Ion channel gating is a rapid, complex process occurring within a few milliseconds and often several gate mechanisms can be found within one protein. For example, the human Connexin 26 alone is known to have plug gating, fast gating, and several chemical gating processes, the first two of which involve conformational changes within the protein [1-3].

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Confocal raman microscopy in VIS for analysing conformational changes in channel proteins. / Kniggendorf, Ann Kathrin; Schmidt, David; Zeilinger, Carsten et al.
2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. 2019. 8872650.

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Kniggendorf, AK, Schmidt, D, Zeilinger, C & Roth, B 2019, Confocal raman microscopy in VIS for analysing conformational changes in channel proteins. in 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019., 8872650, 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019, Munich, Germany, 23 Jun 2019. https://doi.org/10.1109/CLEOE-EQEC.2019.8872650
Kniggendorf, A. K., Schmidt, D., Zeilinger, C., & Roth, B. (2019). Confocal raman microscopy in VIS for analysing conformational changes in channel proteins. In 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019 Article 8872650 https://doi.org/10.1109/CLEOE-EQEC.2019.8872650
Kniggendorf AK, Schmidt D, Zeilinger C, Roth B. Confocal raman microscopy in VIS for analysing conformational changes in channel proteins. In 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. 2019. 8872650 doi: 10.1109/CLEOE-EQEC.2019.8872650
Kniggendorf, Ann Kathrin ; Schmidt, David ; Zeilinger, Carsten et al. / Confocal raman microscopy in VIS for analysing conformational changes in channel proteins. 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. 2019.
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abstract = "Ion channels are crucial proteins of all cells capable of generating electrical signals, responsible for converting chemical or mechanical messages into electrical signals by rapidly altering the ion concentration within the cell upon activation of the channel gate. Ion channel gating is a rapid, complex process occurring within a few milliseconds and often several gate mechanisms can be found within one protein. For example, the human Connexin 26 alone is known to have plug gating, fast gating, and several chemical gating processes, the first two of which involve conformational changes within the protein [1-3].",
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