Details
| Original language | English |
|---|---|
| Article number | 2935 |
| Journal | Molecules |
| Volume | 27 |
| Issue number | 9 |
| Publication status | Published - 4 May 2022 |
Abstract
The present study aimed to assess metabolites heterogeneity among four major Cin-namomum species, including true cinnamon (Cinnamomum verum) and less explored species (C. cas-sia, C. iners, and C. tamala). UPLC-MS led to the annotation of 74 secondary metabolites belonging to different classes, including phenolic acids, tannins, flavonoids, and lignans. A new proanthocy-anidin was identified for the first time in C. tamala, along with several glycosylated flavonoid and dicarboxylic fatty acids reported for the first time in cinnamon. Multivariate data analyses revealed, for cinnamates, an abundance in C. verum versus procyandins, dihydro-coumaroylglycosides, and coumarin in C. cassia. A total of 51 primary metabolites were detected using GC-MS analysis en-compassing different classes, viz. sugars, fatty acids, and sugar alcohols, with true cinnamon from Malaysia suggested as a good sugar source for diabetic patients. Glycerol in C. tamala, erythritol in C. iners, and glucose and fructose in C. verum from Malaysia were major metabolites contributing to the discrimination among species.
Keywords
- chemometrics, Cinnamomum, erythritol, metabolomics, proanthocyanidin
ASJC Scopus subject areas
- Pharmacology, Toxicology and Pharmaceutics(all)
- Drug Discovery
- Chemistry(all)
- Analytical Chemistry
- Chemistry(all)
- Chemistry (miscellaneous)
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Medicine
- Chemistry(all)
- Physical and Theoretical Chemistry
- Pharmacology, Toxicology and Pharmaceutics(all)
- Pharmaceutical Science
- Chemistry(all)
- Organic Chemistry
Sustainable Development Goals
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In: Molecules, Vol. 27, No. 9, 2935, 04.05.2022.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Comparative Metabolite Fingerprinting of Four Different Cinnamon Species Analyzed via UPLC–MS and GC–MS and Chemometric Tools
AU - Farag, Mohamed A.
AU - Kabbash, Eman M.
AU - Mediani, Ahmed
AU - Döll, Stefanie
AU - Esatbeyoglu, Tuba
AU - Afifi, Sherif M.
N1 - Funding Information: Funding: The publication of this article was funded by the Open Access Fund of Leibniz Universität Hannover.
PY - 2022/5/4
Y1 - 2022/5/4
N2 - The present study aimed to assess metabolites heterogeneity among four major Cin-namomum species, including true cinnamon (Cinnamomum verum) and less explored species (C. cas-sia, C. iners, and C. tamala). UPLC-MS led to the annotation of 74 secondary metabolites belonging to different classes, including phenolic acids, tannins, flavonoids, and lignans. A new proanthocy-anidin was identified for the first time in C. tamala, along with several glycosylated flavonoid and dicarboxylic fatty acids reported for the first time in cinnamon. Multivariate data analyses revealed, for cinnamates, an abundance in C. verum versus procyandins, dihydro-coumaroylglycosides, and coumarin in C. cassia. A total of 51 primary metabolites were detected using GC-MS analysis en-compassing different classes, viz. sugars, fatty acids, and sugar alcohols, with true cinnamon from Malaysia suggested as a good sugar source for diabetic patients. Glycerol in C. tamala, erythritol in C. iners, and glucose and fructose in C. verum from Malaysia were major metabolites contributing to the discrimination among species.
AB - The present study aimed to assess metabolites heterogeneity among four major Cin-namomum species, including true cinnamon (Cinnamomum verum) and less explored species (C. cas-sia, C. iners, and C. tamala). UPLC-MS led to the annotation of 74 secondary metabolites belonging to different classes, including phenolic acids, tannins, flavonoids, and lignans. A new proanthocy-anidin was identified for the first time in C. tamala, along with several glycosylated flavonoid and dicarboxylic fatty acids reported for the first time in cinnamon. Multivariate data analyses revealed, for cinnamates, an abundance in C. verum versus procyandins, dihydro-coumaroylglycosides, and coumarin in C. cassia. A total of 51 primary metabolites were detected using GC-MS analysis en-compassing different classes, viz. sugars, fatty acids, and sugar alcohols, with true cinnamon from Malaysia suggested as a good sugar source for diabetic patients. Glycerol in C. tamala, erythritol in C. iners, and glucose and fructose in C. verum from Malaysia were major metabolites contributing to the discrimination among species.
KW - chemometrics
KW - Cinnamomum
KW - erythritol
KW - metabolomics
KW - proanthocyanidin
UR - http://www.scopus.com/inward/record.url?scp=85130056694&partnerID=8YFLogxK
U2 - 10.3390/molecules27092935
DO - 10.3390/molecules27092935
M3 - Article
VL - 27
JO - Molecules
JF - Molecules
SN - 1420-3049
IS - 9
M1 - 2935
ER -