Combining enabling techniques in organic synthesis: Continuous flow processes with heterogenized catalysts

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Original languageEnglish
Pages (from-to)5972-5990
Number of pages19
JournalChemistry - A European Journal
Volume12
Issue number23
Publication statusPublished - 26 Jul 2006

Abstract

The concepts article describes enabling techniques (solid-phase assisted synthesis, new reactor design, microwave irradiation and new solvents) in organic chemistry and emphasizes the combination of several of them for creating new synthetic technology platforms. Particular focus is put on the combination of immobilized catalysts as well as biocatalysts with continuous flow processes. In this context, the PASSflow continuous flow technique fulfils both chemical as well as chemical engineering requirements. It combines reactor design with optimized, monolithic solid phases as well as reversible immobilization techniques for performing small as well as large scale synthesis with heterogenized catalysts under continuous flow conditions.

Keywords

    C-C coupling, Heterogeneous catalysis, Immobilization, Microreactors, Organic chemistry

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Combining enabling techniques in organic synthesis: Continuous flow processes with heterogenized catalysts. / Kirschning, Andreas; Solodenko, Wladimir; Mennecke, Klaas.
In: Chemistry - A European Journal, Vol. 12, No. 23, 26.07.2006, p. 5972-5990.

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