Chondramide C: Synthesis, configurational assignment, and structure-activity relationship studies

Research output: Contribution to journalArticleResearchpeer review

Authors

  • Ulrike Eggert
  • Randi Diestel
  • Florenz Sasse
  • Rolf Jansen
  • Brigitte Kunze
  • Markus Kalesse

External Research Organisations

  • Helmholtz Centre for Infection Research (HZI)
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Details

Original languageEnglish
Pages (from-to)6478-6482
Number of pages5
JournalAngewandte Chemie - International Edition
Volume47
Issue number34
Publication statusPublished - 11 Aug 2008

Abstract

(Chemical Equation Presented) Two solutions for one problem: Of the four isomers of chondramide C synthesized, the two shown in the scheme exhibit nearly the same conformation of the peptide segment and consequently unfold equal biological activities.

Keywords

    Chondramide, Natural products, Structure elucidation, Structure-activity relationships, Total synthesis

ASJC Scopus subject areas

Cite this

Chondramide C: Synthesis, configurational assignment, and structure-activity relationship studies. / Eggert, Ulrike; Diestel, Randi; Sasse, Florenz et al.
In: Angewandte Chemie - International Edition, Vol. 47, No. 34, 11.08.2008, p. 6478-6482.

Research output: Contribution to journalArticleResearchpeer review

Eggert U, Diestel R, Sasse F, Jansen R, Kunze B, Kalesse M. Chondramide C: Synthesis, configurational assignment, and structure-activity relationship studies. Angewandte Chemie - International Edition. 2008 Aug 11;47(34):6478-6482. doi: 10.1002/anie.200801156
Eggert, Ulrike ; Diestel, Randi ; Sasse, Florenz et al. / Chondramide C : Synthesis, configurational assignment, and structure-activity relationship studies. In: Angewandte Chemie - International Edition. 2008 ; Vol. 47, No. 34. pp. 6478-6482.
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