Details
| Original language | English |
|---|---|
| Pages (from-to) | 4053-4055 |
| Number of pages | 3 |
| Journal | Chemical communications |
| Issue number | 39 |
| Publication status | Published - 1 Jan 2007 |
| Externally published | Yes |
Abstract
Isolation and sequencing of a PKS gene isolated from xenovulene-producing cultures of Acremonium strictum indicated the presence of NT-, KS-, AT-, PT-, C-MeT- and R-domains; heterologous expression in Aspergillus oryzae resulted in the production of 3-methylorcinaldehyde, demonstrating the role of the terminal reductase domain in product release.
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Materials Science(all)
- Ceramics and Composites
- Chemistry(all)
- General Chemistry
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Materials Science(all)
- Materials Chemistry
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In: Chemical communications, No. 39, 01.01.2007, p. 4053-4055.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Characterisation of 3-methylorcinaldehyde synthase (MOS) in Acremonium strictum
T2 - First observation of a reductive release mechanism during polyketide biosynthesis
AU - Bailey, Andrew M.
AU - Cox, Russell J.
AU - Harley, Kate
AU - Lazarus, Colin M.
AU - Simpson, Thomas J.
AU - Skellam, Elizabeth
PY - 2007/1/1
Y1 - 2007/1/1
N2 - Isolation and sequencing of a PKS gene isolated from xenovulene-producing cultures of Acremonium strictum indicated the presence of NT-, KS-, AT-, PT-, C-MeT- and R-domains; heterologous expression in Aspergillus oryzae resulted in the production of 3-methylorcinaldehyde, demonstrating the role of the terminal reductase domain in product release.
AB - Isolation and sequencing of a PKS gene isolated from xenovulene-producing cultures of Acremonium strictum indicated the presence of NT-, KS-, AT-, PT-, C-MeT- and R-domains; heterologous expression in Aspergillus oryzae resulted in the production of 3-methylorcinaldehyde, demonstrating the role of the terminal reductase domain in product release.
UR - http://www.scopus.com/inward/record.url?scp=34948833150&partnerID=8YFLogxK
U2 - 10.1039/b708614h
DO - 10.1039/b708614h
M3 - Article
C2 - 17912413
AN - SCOPUS:34948833150
SP - 4053
EP - 4055
JO - Chemical communications
JF - Chemical communications
SN - 1359-7345
IS - 39
ER -