Details
| Original language | English |
|---|---|
| Pages (from-to) | 637-644 |
| Number of pages | 8 |
| Journal | Research in microbiology |
| Volume | 160 |
| Issue number | 9 |
| Publication status | Published - Nov 2009 |
| Externally published | Yes |
Abstract
The Gram-positive model organism Bacillus subtilis is extremely well adapted to changing environmental conditions. The chaperone-protease ClpCP and other AAA+ proteases constitute an important component of the B. subtilis protein quality control system that is essential for survival during stress. In this review, we discuss recent discoveries concerning the molecular mechanism, regulation and localization of proteases and chaperones in B. subtilis.
Keywords
- AAA+, Bacillus subtilis, Heat shock, Hsp100/Clp, Protein quality control, Regulatory proteolysis
ASJC Scopus subject areas
- Immunology and Microbiology(all)
- Microbiology
- Biochemistry, Genetics and Molecular Biology(all)
- Molecular Biology
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In: Research in microbiology, Vol. 160, No. 9, 11.2009, p. 637-644.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Chaperone-protease systems in regulation and protein quality control in Bacillus subtilis
AU - Molière, Noël
AU - Turgay, Kürşad
N1 - Funding information: Work in the Laboratory of K.T. is supported by the Deutsche Forschungsgemeinschaft (SPP 1132, Tu106/6-1).
PY - 2009/11
Y1 - 2009/11
N2 - The Gram-positive model organism Bacillus subtilis is extremely well adapted to changing environmental conditions. The chaperone-protease ClpCP and other AAA+ proteases constitute an important component of the B. subtilis protein quality control system that is essential for survival during stress. In this review, we discuss recent discoveries concerning the molecular mechanism, regulation and localization of proteases and chaperones in B. subtilis.
AB - The Gram-positive model organism Bacillus subtilis is extremely well adapted to changing environmental conditions. The chaperone-protease ClpCP and other AAA+ proteases constitute an important component of the B. subtilis protein quality control system that is essential for survival during stress. In this review, we discuss recent discoveries concerning the molecular mechanism, regulation and localization of proteases and chaperones in B. subtilis.
KW - AAA+
KW - Bacillus subtilis
KW - Heat shock
KW - Hsp100/Clp
KW - Protein quality control
KW - Regulatory proteolysis
UR - http://www.scopus.com/inward/record.url?scp=72049104795&partnerID=8YFLogxK
U2 - 10.1016/j.resmic.2009.08.020
DO - 10.1016/j.resmic.2009.08.020
M3 - Article
C2 - 19781636
AN - SCOPUS:72049104795
VL - 160
SP - 637
EP - 644
JO - Research in microbiology
JF - Research in microbiology
SN - 0923-2508
IS - 9
ER -