Details
| Original language | English |
|---|---|
| Pages (from-to) | 5331-5333 |
| Number of pages | 3 |
| Journal | Chemical communications |
| Volume | 46 |
| Issue number | 29 |
| Publication status | Published - 2010 |
| Externally published | Yes |
Abstract
The in vivo activity of truncated forms of methylorcinaldehyde synthase shows that the synthase retains a hydrolytic release activity in the absence of reductive chain release and that chain-length is not controlled by the reductive release domain; experiments using a methyltransferase inhibitor suggest that methylation occurs prior to aromatisation.
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Materials Science(all)
- Ceramics and Composites
- Chemistry(all)
- General Chemistry
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Materials Science(all)
- Materials Chemistry
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In: Chemical communications, Vol. 46, No. 29, 2010, p. 5331-5333.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Catalytic role of the C-terminal domains of a fungal non-reducing polyketide synthase
AU - Fisch, Katja M.
AU - Skellam, Elizabeth
AU - Ivison, David
AU - Cox, Russell J.
AU - Bailey, Andrew M.
AU - Lazarus, Colin M.
AU - Simpson, Thomas J.
PY - 2010
Y1 - 2010
N2 - The in vivo activity of truncated forms of methylorcinaldehyde synthase shows that the synthase retains a hydrolytic release activity in the absence of reductive chain release and that chain-length is not controlled by the reductive release domain; experiments using a methyltransferase inhibitor suggest that methylation occurs prior to aromatisation.
AB - The in vivo activity of truncated forms of methylorcinaldehyde synthase shows that the synthase retains a hydrolytic release activity in the absence of reductive chain release and that chain-length is not controlled by the reductive release domain; experiments using a methyltransferase inhibitor suggest that methylation occurs prior to aromatisation.
UR - http://www.scopus.com/inward/record.url?scp=77954746891&partnerID=8YFLogxK
U2 - 10.1039/c0cc01162b
DO - 10.1039/c0cc01162b
M3 - Article
C2 - 20552126
AN - SCOPUS:77954746891
VL - 46
SP - 5331
EP - 5333
JO - Chemical communications
JF - Chemical communications
SN - 1359-7345
IS - 29
ER -