Details
| Original language | English |
|---|---|
| Title of host publication | Handbook of Biomineralization |
| Subtitle of host publication | Biological Aspects and Structure Formation |
| Publisher | Wiley - VCH Verlag GmbH & CO. KGaA |
| Pages | 35-48 |
| Number of pages | 14 |
| Volume | 3 |
| ISBN (print) | 9783527316410 |
| Publication status | Published - 20 Mar 2008 |
Abstract
Bones are living organs that have the ability to adapt themselves to their mechanical demands. This phenomenon is of major importance in endoprosthetics. Following an artificial implant, the bone is stressed in a non-physiological manner, and this causes bone remodeling. Computational methods are available to predict this behavior, which in turn allows the optimization of prosthesis design such that the surgeon can identify the best available implant for an individual patient's condition. However, many uncertainties are encountered when quantifying the mechanical loading conditions and the overall mechanical properties of bone tissue. The concept of statically equivalent loads is stated, where the boundary conditions are computed by an inverse simulation from computed tomography data. The mechanical properties of cortical bone are obtained using a micro-mechanical approach, with several stages of homogenization. Moreover, the process of mechanotransduction may be simulated by using this multi-scale approach.
Keywords
- Finite element techniques, Hip-joint endoprosthetics, Multi-scale methods, Stress-adaptive bone remodeling
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- General Biochemistry,Genetics and Molecular Biology
Cite this
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Handbook of Biomineralization: Biological Aspects and Structure Formation. Vol. 3 Wiley - VCH Verlag GmbH & CO. KGaA, 2008. p. 35-48.
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Biomechanics of Bones
T2 - Modeling and Computation of Bone Remodeling
AU - Nackenhorst, Udo
PY - 2008/3/20
Y1 - 2008/3/20
N2 - Bones are living organs that have the ability to adapt themselves to their mechanical demands. This phenomenon is of major importance in endoprosthetics. Following an artificial implant, the bone is stressed in a non-physiological manner, and this causes bone remodeling. Computational methods are available to predict this behavior, which in turn allows the optimization of prosthesis design such that the surgeon can identify the best available implant for an individual patient's condition. However, many uncertainties are encountered when quantifying the mechanical loading conditions and the overall mechanical properties of bone tissue. The concept of statically equivalent loads is stated, where the boundary conditions are computed by an inverse simulation from computed tomography data. The mechanical properties of cortical bone are obtained using a micro-mechanical approach, with several stages of homogenization. Moreover, the process of mechanotransduction may be simulated by using this multi-scale approach.
AB - Bones are living organs that have the ability to adapt themselves to their mechanical demands. This phenomenon is of major importance in endoprosthetics. Following an artificial implant, the bone is stressed in a non-physiological manner, and this causes bone remodeling. Computational methods are available to predict this behavior, which in turn allows the optimization of prosthesis design such that the surgeon can identify the best available implant for an individual patient's condition. However, many uncertainties are encountered when quantifying the mechanical loading conditions and the overall mechanical properties of bone tissue. The concept of statically equivalent loads is stated, where the boundary conditions are computed by an inverse simulation from computed tomography data. The mechanical properties of cortical bone are obtained using a micro-mechanical approach, with several stages of homogenization. Moreover, the process of mechanotransduction may be simulated by using this multi-scale approach.
KW - Finite element techniques
KW - Hip-joint endoprosthetics
KW - Multi-scale methods
KW - Stress-adaptive bone remodeling
UR - http://www.scopus.com/inward/record.url?scp=84889990604&partnerID=8YFLogxK
U2 - 10.1002/9783527619443.ch47
DO - 10.1002/9783527619443.ch47
M3 - Contribution to book/anthology
AN - SCOPUS:84889990604
SN - 9783527316410
VL - 3
SP - 35
EP - 48
BT - Handbook of Biomineralization
PB - Wiley - VCH Verlag GmbH & CO. KGaA
ER -