Details
| Original language | English |
|---|---|
| Pages (from-to) | 315-318 |
| Number of pages | 4 |
| Journal | Sensors and Actuators: B. Chemical |
| Volume | 4 |
| Issue number | 3-4 |
| Publication status | Published - Jun 1991 |
Abstract
The application of enzyme-modified field-effect transistors (BioFETs) in biotechnological process control is presented. Penicillin, glucose and urea are detected with these devices in cultivation media and on-line in biotechnological processes. In these applications, the BioFETs are used as detectors in flow injection analysis (FIA) systems. Special flow cells with a small volume, constructed for this purpose, guarantee an optimum sample transport to the sensor. Therefore, 15-20 determinations per hour can be performed. The BioFET/FIA system gives good results for the on-line monitoring of glucose and urea during cultivations of S. cerevisiae and E. coli in different types of bioreactors.
ASJC Scopus subject areas
- Materials Science(all)
- Electronic, Optical and Magnetic Materials
- Physics and Astronomy(all)
- Instrumentation
- Physics and Astronomy(all)
- Condensed Matter Physics
- Materials Science(all)
- Surfaces, Coatings and Films
- Materials Science(all)
- Metals and Alloys
- Engineering(all)
- Electrical and Electronic Engineering
- Materials Science(all)
- Materials Chemistry
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In: Sensors and Actuators: B. Chemical, Vol. 4, No. 3-4, 06.1991, p. 315-318.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Bio-field-effect Transistors for Process Control in Biotechnology
AU - Brand, U.
AU - Reinhardt, B.
AU - Rüther, F.
AU - Scheper, T.
AU - Schügerl, K.
PY - 1991/6
Y1 - 1991/6
N2 - The application of enzyme-modified field-effect transistors (BioFETs) in biotechnological process control is presented. Penicillin, glucose and urea are detected with these devices in cultivation media and on-line in biotechnological processes. In these applications, the BioFETs are used as detectors in flow injection analysis (FIA) systems. Special flow cells with a small volume, constructed for this purpose, guarantee an optimum sample transport to the sensor. Therefore, 15-20 determinations per hour can be performed. The BioFET/FIA system gives good results for the on-line monitoring of glucose and urea during cultivations of S. cerevisiae and E. coli in different types of bioreactors.
AB - The application of enzyme-modified field-effect transistors (BioFETs) in biotechnological process control is presented. Penicillin, glucose and urea are detected with these devices in cultivation media and on-line in biotechnological processes. In these applications, the BioFETs are used as detectors in flow injection analysis (FIA) systems. Special flow cells with a small volume, constructed for this purpose, guarantee an optimum sample transport to the sensor. Therefore, 15-20 determinations per hour can be performed. The BioFET/FIA system gives good results for the on-line monitoring of glucose and urea during cultivations of S. cerevisiae and E. coli in different types of bioreactors.
UR - http://www.scopus.com/inward/record.url?scp=0026172380&partnerID=8YFLogxK
U2 - 10.1016/0925-4005(91)80129-8
DO - 10.1016/0925-4005(91)80129-8
M3 - Article
AN - SCOPUS:0026172380
VL - 4
SP - 315
EP - 318
JO - Sensors and Actuators: B. Chemical
JF - Sensors and Actuators: B. Chemical
SN - 0925-4005
IS - 3-4
ER -