Details
| Original language | English |
|---|---|
| Pages (from-to) | S410-S414 |
| Journal | Biomedizinische Technik |
| Volume | 59 |
| Issue number | s1 |
| Publication status | Published - 1 Oct 2014 |
Abstract
Electrospinning is a production process for fibrous scaffolds for tissue engineering. Various electrospinning devices already exist. However, none of the devices can be easily integrated into a line production for heart valve scaffolds. In this work, concepts have been developed for setting up a line production consisting of several electrospinning and laser manufacturing cells. The heart valve cusps are electrospun and then laser cut. The cusps are together with a hollow cylinder laser welded to form a heart valve scaffold. The scaffold is finally packed. Additionally, a control for spinneret positioning and the shutter of the electrospinning device was engineered and coded. This brings the electrospinning device one step closer to full automation. The interface was tested during electrospinning production of various scaffolds.
Keywords
- Automation, Electrospinning, Heart Valve, Scaffold
ASJC Scopus subject areas
- Engineering(all)
- Biomedical Engineering
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In: Biomedizinische Technik, Vol. 59, No. s1, 01.10.2014, p. S410-S414.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Automatized production of scaffolds for heart valve tissue engineering
AU - Hoheisel, A. L.
AU - Zernetsch, H.
AU - Glasmacher, B.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - Electrospinning is a production process for fibrous scaffolds for tissue engineering. Various electrospinning devices already exist. However, none of the devices can be easily integrated into a line production for heart valve scaffolds. In this work, concepts have been developed for setting up a line production consisting of several electrospinning and laser manufacturing cells. The heart valve cusps are electrospun and then laser cut. The cusps are together with a hollow cylinder laser welded to form a heart valve scaffold. The scaffold is finally packed. Additionally, a control for spinneret positioning and the shutter of the electrospinning device was engineered and coded. This brings the electrospinning device one step closer to full automation. The interface was tested during electrospinning production of various scaffolds.
AB - Electrospinning is a production process for fibrous scaffolds for tissue engineering. Various electrospinning devices already exist. However, none of the devices can be easily integrated into a line production for heart valve scaffolds. In this work, concepts have been developed for setting up a line production consisting of several electrospinning and laser manufacturing cells. The heart valve cusps are electrospun and then laser cut. The cusps are together with a hollow cylinder laser welded to form a heart valve scaffold. The scaffold is finally packed. Additionally, a control for spinneret positioning and the shutter of the electrospinning device was engineered and coded. This brings the electrospinning device one step closer to full automation. The interface was tested during electrospinning production of various scaffolds.
KW - Automation
KW - Electrospinning
KW - Heart Valve
KW - Scaffold
UR - http://www.scopus.com/inward/record.url?scp=84908202291&partnerID=8YFLogxK
U2 - 10.1515/bmt-2014-5005
DO - 10.1515/bmt-2014-5005
M3 - Article
AN - SCOPUS:84908202291
VL - 59
SP - S410-S414
JO - Biomedizinische Technik
JF - Biomedizinische Technik
SN - 0013-5585
IS - s1
ER -