Details
| Original language | English |
|---|---|
| Title of host publication | Tunable Hydrogels |
| Subtitle of host publication | Smart Materials for Biomedical Applications |
| Publisher | Springer Science and Business Media Deutschland GmbH |
| Pages | 147-168 |
| Number of pages | 22 |
| Edition | 1 |
| ISBN (electronic) | 978-3-030-76769-3 |
| ISBN (print) | 978-3-030-76768-6, 978-3-030-76771-6 |
| Publication status | Published - 2021 |
Publication series
| Name | Advances in Biochemical Engineering/Biotechnology |
|---|---|
| Volume | 178 |
| ISSN (Print) | 0724-6145 |
| ISSN (electronic) | 1616-8542 |
Abstract
Hydrogels have attracted much attention especially due to their biocompatibility and their potential for stimulus responsiveness. By combining hydrogels with aptamers, biological recognition and responsiveness can be added to hydrogels, thereby opening path to advanced applications in biosensing and biomedicine. Within this chapter aptamers will be introduced and their contributions to biological responsiveness of hydrogels will be described. Especially the aptamer-based mechanisms that result in biological responsiveness will be explained and examples for the application of these mechanisms will be given ranging from rather simple sensing approaches to advanced materials for tissue engineering and drug delivery. Since aptamers are not only highly specific bioreceptors, but represent switchable structures that can be easily manipulated using well-known DNA techniques, the combination of aptamers and hydrogels facilitates the rational design of well-programmable and target-responsive smart hydrogels.
Keywords
- Aptamers, Biomedicine, Biosensing, Hydrogels, Target-responsive hydrogels
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Biotechnology
- Chemical Engineering(all)
- Bioengineering
- Immunology and Microbiology(all)
- Applied Microbiology and Biotechnology
Cite this
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Tunable Hydrogels: Smart Materials for Biomedical Applications. 1. ed. Springer Science and Business Media Deutschland GmbH, 2021. p. 147-168 (Advances in Biochemical Engineering/Biotechnology; Vol. 178).
Research output: Chapter in book/report/conference proceeding › Contribution to book/anthology › Research › peer review
}
TY - CHAP
T1 - Aptamer-Modified Hydrogels
AU - Walter, Johanna Gabriela
PY - 2021
Y1 - 2021
N2 - Hydrogels have attracted much attention especially due to their biocompatibility and their potential for stimulus responsiveness. By combining hydrogels with aptamers, biological recognition and responsiveness can be added to hydrogels, thereby opening path to advanced applications in biosensing and biomedicine. Within this chapter aptamers will be introduced and their contributions to biological responsiveness of hydrogels will be described. Especially the aptamer-based mechanisms that result in biological responsiveness will be explained and examples for the application of these mechanisms will be given ranging from rather simple sensing approaches to advanced materials for tissue engineering and drug delivery. Since aptamers are not only highly specific bioreceptors, but represent switchable structures that can be easily manipulated using well-known DNA techniques, the combination of aptamers and hydrogels facilitates the rational design of well-programmable and target-responsive smart hydrogels.
AB - Hydrogels have attracted much attention especially due to their biocompatibility and their potential for stimulus responsiveness. By combining hydrogels with aptamers, biological recognition and responsiveness can be added to hydrogels, thereby opening path to advanced applications in biosensing and biomedicine. Within this chapter aptamers will be introduced and their contributions to biological responsiveness of hydrogels will be described. Especially the aptamer-based mechanisms that result in biological responsiveness will be explained and examples for the application of these mechanisms will be given ranging from rather simple sensing approaches to advanced materials for tissue engineering and drug delivery. Since aptamers are not only highly specific bioreceptors, but represent switchable structures that can be easily manipulated using well-known DNA techniques, the combination of aptamers and hydrogels facilitates the rational design of well-programmable and target-responsive smart hydrogels.
KW - Aptamers
KW - Biomedicine
KW - Biosensing
KW - Hydrogels
KW - Target-responsive hydrogels
UR - http://www.scopus.com/inward/record.url?scp=85107375431&partnerID=8YFLogxK
U2 - 10.1007/10_2021_166
DO - 10.1007/10_2021_166
M3 - Contribution to book/anthology
C2 - 33796881
AN - SCOPUS:85107375431
SN - 978-3-030-76768-6
SN - 978-3-030-76771-6
T3 - Advances in Biochemical Engineering/Biotechnology
SP - 147
EP - 168
BT - Tunable Hydrogels
PB - Springer Science and Business Media Deutschland GmbH
ER -