Analyzing randomized dose finding studies with a primary and a secondary endpoint

Research output: Contribution to journal › Article › Research › peer review

Authors

  • Ludwig A. Hothorn
  • Gernot Wassmer

Research Organisations

External Research Organisations

  • University of Cologne
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Details

Original languageEnglish
Pages (from-to)301-305
Number of pages5
JournalJournal of Biopharmaceutical Statistics
Volume13
Issue number2
Publication statusPublished - 4 Jan 2003

Abstract

The identification of the minimum effective dose for both the primary and secondary endpoint under a priori importance ordering assumption is described. Stepwise testing procedures, which conditionally test each elementary hypotheses at level α, but control the experimentwise Type I error rate, can be used.

Keywords

    Dose finding trial, Intersection-union test, Multiple endpoints

ASJC Scopus subject areas

Cite this

Analyzing randomized dose finding studies with a primary and a secondary endpoint. / Hothorn, Ludwig A.; Wassmer, Gernot.
In: Journal of Biopharmaceutical Statistics, Vol. 13, No. 2, 04.01.2003, p. 301-305.

Research output: Contribution to journal › Article › Research › peer review

Hothorn LA, Wassmer G. Analyzing randomized dose finding studies with a primary and a secondary endpoint. Journal of Biopharmaceutical Statistics. 2003 Jan 4;13(2):301-305. doi: 10.1081/BIP-120019273
Hothorn, Ludwig A. ; Wassmer, Gernot. / Analyzing randomized dose finding studies with a primary and a secondary endpoint. In: Journal of Biopharmaceutical Statistics. 2003 ; Vol. 13, No. 2. pp. 301-305.
Download
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