Details
| Original language | English |
|---|---|
| Pages (from-to) | 461-466 |
| Number of pages | 6 |
| Journal | Synthesis |
| Issue number | 3 |
| Publication status | Published - 11 Jan 2006 |
Abstract
A convenient one-step transformation of primary and secondary amines into the corresponding unprotected guanidines using 4-benzyl-3,5-dimethyl-1H- pyrazole-1-carboxamidine and its polymer-bound variant is described. The scopes and limitations of the method, the microwave-assistance of amidination as well as a recycling protocol are examined.
Keywords
- Amines, Guanidines, Microwave-assisted synthesis, Polymer-bound reagent, Reagent regeneration
ASJC Scopus subject areas
- Chemical Engineering(all)
- Catalysis
- Chemistry(all)
- Organic Chemistry
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In: Synthesis, No. 3, 11.01.2006, p. 461-466.
Research output: Contribution to journal › Article › Research › peer review
}
TY - JOUR
T1 - Amidination of amines under microwave conditions using recyclable polymer-bound 1H-pyrazole-1-carboxamidine
AU - Solodenko, Wladimir
AU - Bröker, Patrick
AU - Messinger, Josef
AU - Schön, Uwe
AU - Kirschning, Andreas
PY - 2006/1/11
Y1 - 2006/1/11
N2 - A convenient one-step transformation of primary and secondary amines into the corresponding unprotected guanidines using 4-benzyl-3,5-dimethyl-1H- pyrazole-1-carboxamidine and its polymer-bound variant is described. The scopes and limitations of the method, the microwave-assistance of amidination as well as a recycling protocol are examined.
AB - A convenient one-step transformation of primary and secondary amines into the corresponding unprotected guanidines using 4-benzyl-3,5-dimethyl-1H- pyrazole-1-carboxamidine and its polymer-bound variant is described. The scopes and limitations of the method, the microwave-assistance of amidination as well as a recycling protocol are examined.
KW - Amines
KW - Guanidines
KW - Microwave-assisted synthesis
KW - Polymer-bound reagent
KW - Reagent regeneration
UR - http://www.scopus.com/inward/record.url?scp=32644448194&partnerID=8YFLogxK
U2 - 10.1055/s-2006-926284
DO - 10.1055/s-2006-926284
M3 - Article
AN - SCOPUS:32644448194
SP - 461
EP - 466
JO - Synthesis
JF - Synthesis
SN - 0039-7881
IS - 3
ER -