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Algorithm to extract the shortest linear edge and the longest diagonal of single isolated human insulin crystals for in-situ microscopy

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  • Universidad de Costa Rica

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Original languageEnglish
Title of host publication2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (electronic)9781467378390
Publication statusPublished - 17 Dec 2015
Event2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control (CCE) - Mexico City, Mexico
Duration: 28 Oct 201530 Oct 2015

Abstract

In this contribution, an algorithm is presented, which is able to extract the shortest linear edge and the longest diagonal of each single isolated human insulin crystal region, which is found in an arbitrary image captured by an insitu microscope inside of a reactor, where a human insulin crystallization processes is taking place. First, the image regions of the single isolated crystals are segmented by combining three different techniques: thresholding, single nearest prototype classification and snakes. Then, the image positions of the vertices of each single isolated crystal region are determined by using the Hough Transformation. Finally, both the shortest linear edge and the longest diagonal of each single isolated crystal region are extracted by measuring and comparing distances between the found image positions of the single isolated crystal region vertices. Experimental results revealed an absolute length error of 4.18 percent and 2.32 percent of the extracted shortest linear edges and the extracted longest diagonals, respectively.

Cite this

Algorithm to extract the shortest linear edge and the longest diagonal of single isolated human insulin crystals for in-situ microscopy. / Martinez, G.; Lindner, P.; Bluma, A. et al.
2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2015. Institute of Electrical and Electronics Engineers Inc., 2015.

Research output: Chapter in book/report/conference proceedingConference contributionResearchpeer review

Martinez, G, Lindner, P, Bluma, A & Scheper, T 2015, Algorithm to extract the shortest linear edge and the longest diagonal of single isolated human insulin crystals for in-situ microscopy. in 2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2015. Institute of Electrical and Electronics Engineers Inc., 2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control (CCE), Mexico City, Mexico, 28 Oct 2015. https://doi.org/10.1109/iceee.2015.7357903
Martinez, G., Lindner, P., Bluma, A., & Scheper, T. (2015). Algorithm to extract the shortest linear edge and the longest diagonal of single isolated human insulin crystals for in-situ microscopy. In 2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2015 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/iceee.2015.7357903
Martinez G, Lindner P, Bluma A, Scheper T. Algorithm to extract the shortest linear edge and the longest diagonal of single isolated human insulin crystals for in-situ microscopy. In 2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2015. Institute of Electrical and Electronics Engineers Inc. 2015 doi: 10.1109/iceee.2015.7357903
Martinez, G. ; Lindner, P. ; Bluma, A. et al. / Algorithm to extract the shortest linear edge and the longest diagonal of single isolated human insulin crystals for in-situ microscopy. 2015 12th International Conference on Electrical Engineering, Computing Science and Automatic Control, CCE 2015. Institute of Electrical and Electronics Engineers Inc., 2015.
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