Acyl palladium species in synthesis: Single-step synthesis of α,β-unsaturated ketones from acid chlorides

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  • University of Bristol
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Original languageEnglish
Pages (from-to)229-232
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number2
Publication statusPublished - 2007
Externally publishedYes

Abstract

Conditions are reported for the facile, one-pot synthesis of α,β-unsaturated ketones via the palladium-catalysed cross-coupling of acyl chlorides with hydrozirconated acetylenes, and its use in the 2-step synthesis of d-5-O-benzyl deoxyxylulose.

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Acyl palladium species in synthesis: Single-step synthesis of α,β-unsaturated ketones from acid chlorides. / Cox, Russell J.; Evitt, Andrew S.
In: Organic and Biomolecular Chemistry, Vol. 5, No. 2, 2007, p. 229-232.

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AB - Conditions are reported for the facile, one-pot synthesis of α,β-unsaturated ketones via the palladium-catalysed cross-coupling of acyl chlorides with hydrozirconated acetylenes, and its use in the 2-step synthesis of d-5-O-benzyl deoxyxylulose.

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