Details
| Original language | English |
|---|---|
| Title of host publication | Bildverarbeitung fur die Medizin 2005 |
| Subtitle of host publication | Algorithmen - Systeme - Anwendungen, BVM 2005 - Proceedings des Workshops |
| Pages | 385-389 |
| Number of pages | 5 |
| Publication status | Published - 2005 |
| Externally published | Yes |
| Event | Workshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2005 - Workshop on Image Processing for Medicine: Algorithms - Systems - Applications, BVM 2005 - Heidelberg, Germany Duration: 13 Mar 2005 → 15 Mar 2005 |
Publication series
| Name | Informatik aktuell |
|---|---|
| ISSN (Print) | 1431-472X |
Abstract
Differential gene expression experiments using DNA microar-ray technology yield raw data in the form of fluorescence images which must be segmented and quantified to extract the expression data. This work proposes an active contour method for the precise segmentation of DNA spots in microarray images as well as an estimator for the unspecific background intensity. The proposed methods are compared to commonly employed methods using data from experiments where some knowledge of the studied biological systems exists.
ASJC Scopus subject areas
- Mathematics(all)
- Modelling and Simulation
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Bildverarbeitung fur die Medizin 2005: Algorithmen - Systeme - Anwendungen, BVM 2005 - Proceedings des Workshops. 2005. p. 385-389 (Informatik aktuell).
Research output: Chapter in book/report/conference proceeding › Conference contribution › Research › peer review
}
TY - GEN
T1 - Active Contours and a Background Intensity Estimator for Analysis of Microarray Spots
AU - Katzer, M.
AU - Horvay, K.
AU - Küster, H.
AU - Landgrebe, J.
AU - Loop, S.
AU - Spielbauer, B.
AU - Brunner, E.
AU - Pieler, T.
PY - 2005
Y1 - 2005
N2 - Differential gene expression experiments using DNA microar-ray technology yield raw data in the form of fluorescence images which must be segmented and quantified to extract the expression data. This work proposes an active contour method for the precise segmentation of DNA spots in microarray images as well as an estimator for the unspecific background intensity. The proposed methods are compared to commonly employed methods using data from experiments where some knowledge of the studied biological systems exists.
AB - Differential gene expression experiments using DNA microar-ray technology yield raw data in the form of fluorescence images which must be segmented and quantified to extract the expression data. This work proposes an active contour method for the precise segmentation of DNA spots in microarray images as well as an estimator for the unspecific background intensity. The proposed methods are compared to commonly employed methods using data from experiments where some knowledge of the studied biological systems exists.
UR - http://www.scopus.com/inward/record.url?scp=84879911500&partnerID=8YFLogxK
U2 - 10.1007/3-540-26431-0_79
DO - 10.1007/3-540-26431-0_79
M3 - Conference contribution
AN - SCOPUS:84879911500
SN - 3540250522
SN - 9783540250524
T3 - Informatik aktuell
SP - 385
EP - 389
BT - Bildverarbeitung fur die Medizin 2005
T2 - Workshops Bildverarbeitung fur die Medizin: Algorithmen - Systeme - Anwendungen, BVM 2005 - Workshop on Image Processing for Medicine: Algorithms - Systems - Applications, BVM 2005
Y2 - 13 March 2005 through 15 March 2005
ER -