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Original language | English |
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Publication status | E-pub ahead of print - 2 Jan 2021 |
Abstract
Keywords
- stat.AP
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2021.
Research output: Working paper/Preprint › Preprint
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TY - UNPB
T1 - A statistical method for estimating the no-observed-adverse-event-level
AU - Hothorn, Ludwig A.
N1 - 4 data examples, with raw data and R-code
PY - 2021/1/2
Y1 - 2021/1/2
N2 - In toxicological risk assessment the benchmark dose (BMD) is recommended instead of the no-observed-adverse effect-level (NOAEL). Still a simple test procedure to estimate NOAEL is proposed here, explaining its advantages and disadvantages. Versatile applicability is illustrated using four different data examples of selected in vivo toxicity bioassays.
AB - In toxicological risk assessment the benchmark dose (BMD) is recommended instead of the no-observed-adverse effect-level (NOAEL). Still a simple test procedure to estimate NOAEL is proposed here, explaining its advantages and disadvantages. Versatile applicability is illustrated using four different data examples of selected in vivo toxicity bioassays.
KW - stat.AP
M3 - Preprint
BT - A statistical method for estimating the no-observed-adverse-event-level
ER -